ethyl 4-carbamoyl-3-methyl-5-(9H-xanthene-9-carbonylamino)thiophene-2-carboxylate

Base Information

Chemical Name:ethyl 4-carbamoyl-3-methyl-5-(9H-xanthene-9-carbonylamino)thiophene-2-carboxylate
CAS No.:5698-18-0
Molecular Formula:C23H20N2O5S
Molecular Weight:436.4803
Hs Code.:
DSSTox Substance ID:DTXSID60361109
Wikidata:Q82143250

Synonyms:5698-18-0;ethyl 4-carbamoyl-3-methyl-5-(9H-xanthene-9-carbonylamino)thiophene-2-carboxylate;ethyl 4-(aminocarbonyl)-3-methyl-5-[(9H-xanthen-9-ylcarbonyl)amino]-2-thiophenecarboxylate;CBMicro_028725;Oprea1_348569;DTXSID60361109;STK426498;AKOS001690482;BIM-0028522.P001;AK-968/12101029;ethyl 4-carbamoyl-3-methyl-5-[(9H-xanthen-9-ylcarbonyl)amino]thiophene-2-carboxylate

Suppliers and Price of ethyl 4-carbamoyl-3-methyl-5-(9H-xanthene-9-carbonylamino)thiophene-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 4-carbamoyl-3-methyl-5-(9H-xanthene-9-carbonylamino)thiophene-2-carboxylate

Chemical Property:

Vapor Pressure:1.28E-14mmHg at 25°C
Boiling Point:605.6°Cat760mmHg
Flash Point:320.1°C
Density:1.387g/cm³
XLogP3:4.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:436.10929292
Heavy Atom Count:31
Complexity:682

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(C(=C(S1)NC(=O)C2C3=CC=CC=C3OC4=CC=CC=C24)C(=O)N)C

Technology Process of ethyl 4-carbamoyl-3-methyl-5-(9H-xanthene-9-carbonylamino)thiophene-2-carboxylate

There total 8 articles about ethyl 4-carbamoyl-3-methyl-5-(9H-xanthene-9-carbonylamino)thiophene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6047-62-7
1,3,4,6-tetrahydro-azepino[4,3,2-cd]indol-5-one

: 5698-18-0
3,4,5,6-tetrahydro-1H-azepino[4,3,2-cd]indole

Guidance literature:: 1,3,4,6-tetrahydro-azepino[4,3,2-cd]indol-5-one; With lithium aluminium tetrahydride; In tetrahydrofuran; for 6h; Heating / reflux;

With sodium hydroxide; In tetrahydrofuran; water; at 0 - 20 ℃;

Reference yield:

: 4769-97-5
4-nitro-1H-indoIe

: 5698-18-0
3,4,5,6-tetrahydro-1H-azepino[4,3,2-cd]indole

Guidance literature:: Multi-step reaction with 7 steps

1.1: acetic acid

2.1: benzene / Heating / reflux

3.1: hydrogen / palladium on activated charcoal / ethanol

4.1: 200 - 220 °C / Neat (no solvent)

5.1: potassium hydroxide / water / Heating / reflux

6.1: 150 - 170 °C / Neat (no solvent)

7.1: lithium aluminium tetrahydride / tetrahydrofuran / 6 h / Heating / reflux

7.2: 0 - 20 °C

With potassium hydroxide; lithium aluminium tetrahydride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol; water; acetic acid; benzene;

Reference yield:

: 7150-46-1
4-nitrogramine

: 5698-18-0
3,4,5,6-tetrahydro-1H-azepino[4,3,2-cd]indole

Guidance literature:: Multi-step reaction with 6 steps

1.1: benzene / Heating / reflux

2.1: hydrogen / palladium on activated charcoal / ethanol

3.1: 200 - 220 °C / Neat (no solvent)

4.1: potassium hydroxide / water / Heating / reflux

5.1: 150 - 170 °C / Neat (no solvent)

6.1: lithium aluminium tetrahydride / tetrahydrofuran / 6 h / Heating / reflux

6.2: 0 - 20 °C

With potassium hydroxide; lithium aluminium tetrahydride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol; water; benzene;