Ethanone, 1-(2,5-dimethoxyphenyl)-2-(triphenylphosphoranylidene)-

Base Information

Chemical Name:Ethanone, 1-(2,5-dimethoxyphenyl)-2-(triphenylphosphoranylidene)-
CAS No.:141957-50-8
Molecular Formula:C28H25O3P
Molecular Weight:440.478
Hs Code.:
DSSTox Substance ID:DTXSID20569023
Nikkaji Number:J2.479.292G
Wikidata:Q82455720
Mol file:141957-50-8.mol

Synonyms:141957-50-8;1-(2,5-Dimethoxyphenyl)-2-(triphenyl-lambda~5~-phosphanylidene)ethan-1-one;DTXSID20569023;1-(2,5-Dimethoxyphenyl)-2-(triphenylphosphoranylidene)ethanone

Suppliers and Price of Ethanone, 1-(2,5-dimethoxyphenyl)-2-(triphenylphosphoranylidene)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Ethanone, 1-(2,5-dimethoxyphenyl)-2-(triphenylphosphoranylidene)-

Chemical Property:

XLogP3:5.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:440.15413165
Heavy Atom Count:32
Complexity:589

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)OC)C(=O)C=P(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of Ethanone, 1-(2,5-dimethoxyphenyl)-2-(triphenylphosphoranylidene)-

There total 1 articles about Ethanone, 1-(2,5-dimethoxyphenyl)-2-(triphenylphosphoranylidene)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 2785-98-0
2,5-dimethoxybenzoic acid

: 36050-78-9
Bis(trimethylsilyl)methylidene triphenylphosphorane

: 141957-50-8
Ph₃P=CHC(O)C₆H₃-2,5-(OMe)2

Guidance literature:: In tetrahydrofuran; 1) RT, 30 min, 2) reflux, 3-4 d;

Reference yield: 91.0%

: 1003-09-4
2-bromothiophene

: 141957-50-8
Ph₃P=CHC(O)C₆H₃-2,5-(OMe)2

: (5-formylthiophen-2-yl)boronic acid

: (E)-1-(4'-thienyl-2-ylphenyl)-2-(2''',5'''-dimethoxybenzoyl)ethene

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; at 75 ℃; for 10h;
DOI:10.1039/b516724h

Reference yield: 77.0%

: 3375-31-3
palladium diacetate

: 141957-50-8
Ph₃P=CHC(O)C₆H₃-2,5-(OMe)2

: 944937-38-6,944735-14-2
[Pd(μ-Cl)(C,C-[C6H4(PPh2CHC(O)C6H3-2,5-(OMe)2)-2])]2

Guidance literature:: In dichloromethane; byproducts: CH3COOH, LiO2CCH3; Pd salt added to a soln. of ligand, refluxed, evapd., dissolved in MeOH,treated with LiCl, stirred at room temp.; filtered, washed (MeOH, Et2O), dried by suction; obtained as 1.25/1 mixt. of diastereomers; elem. anal.;
DOI:10.1021/om7002877