7-Chloro-1H-indole-2-carboxylic acid

Base Information

Chemical Name:7-Chloro-1H-indole-2-carboxylic acid
CAS No.:28899-75-4
Molecular Formula:C9H6 Cl N O2
Molecular Weight:195.605
Hs Code.:2933990090
European Community (EC) Number:249-296-5
DSSTox Substance ID:DTXSID40183088
Nikkaji Number:J286.476B
Wikidata:Q83053816
ChEMBL ID:CHEMBL430815
Mol file:28899-75-4.mol

Synonyms:7-Chloro-1H-indole-2-carboxylic acid;28899-75-4;7-Chloroindole-2-carboxylic acid;1H-Indole-2-carboxylic acid, 7-chloro-;EINECS 249-296-5;MFCD02664428;1H-INDOLE-2-CARBOXYLIC ACID,7-CHLORO-;CHEMBL430815;SCHEMBL1144741;7-chloro-2-indolecarboxylic acid;AMY4393;DTXSID40183088;BBL022253;STK501549;AKOS005144107;SB75189;NCGC00340453-01;DS-14876;BB 0248937;CS-0119394;FT-0679058;EN300-340368;AB01333411-02;7-Chloro-1H-indole-2-carboxylic acid, AldrichCPR;A856700

Suppliers and Price of 7-Chloro-1H-indole-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-Chloro-1H-indole-2-carboxylicacid
100mg
$ 45.00

Matrix Scientific
7-Chloro-1H-indole-2-carboxylic acid
500mg
$ 126.00

Labseeker
1H-INDOLE-2-CARBOXYLICACID,7-CHLORO- 95
5g
$ 462.00

Crysdot
7-Chloro-1H-indole-2-carboxylicacid 95+%
5g
$ 353.00

Chemenu
7-chloro-1H-indole-2-carboxylicacid 95%
10g
$ 842.00

Chemenu
7-chloro-1H-indole-2-carboxylicacid 95%
5g
$ 468.00

Chemenu
7-chloro-1H-indole-2-carboxylicacid 95%
1g
$ 128.00

Biosynth Carbosynth
7-Chloro-1H-indole-2-carboxylic acid
2 g
$ 289.00

Biosynth Carbosynth
7-Chloro-1H-indole-2-carboxylic acid
1 g
$ 170.00

Biosynth Carbosynth
7-Chloro-1H-indole-2-carboxylic acid
500 mg
$ 100.00

Total 34 raw suppliers

Chemical Property of 7-Chloro-1H-indole-2-carboxylic acid

Chemical Property:

Vapor Pressure:7.12E-09mmHg at 25°C
Boiling Point:449.7°Cat760mmHg
PKA:4.23±0.30(Predicted)
Flash Point:225.8°C
PSA：53.09000
Density:1.548g/cm³
LogP:2.51950
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:195.0087061
Heavy Atom Count:13
Complexity:222

Purity/Quality:

97% ^*data from raw suppliers

7-Chloro-1H-indole-2-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C(=C1)Cl)NC(=C2)C(=O)O

Technology Process of 7-Chloro-1H-indole-2-carboxylic acid

There total 7 articles about 7-Chloro-1H-indole-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 43142-64-9
7-Chloro-1H-indole-2-carboxylic acid ethyl ester

: 28899-75-4
7-Chloro-1H-indole-2-carboxylic acid

Guidance literature:: With lithium hydroxide; In ethanol; water; at 20 ℃; for 18h;
DOI:10.1021/jm0341047

Reference yield:

: 77158-85-1
(3-chloro-2-nitro-phenyl)-pyruvic acid

: 28899-75-4
7-Chloro-1H-indole-2-carboxylic acid

Guidance literature:: With ammonium hydroxide; iron(II) hydroxide;
DOI:10.1021/ja01626a071

Reference yield:

: 41052-75-9
o-chlorophenylhydrazine hydrochloride

: 28899-75-4
7-Chloro-1H-indole-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid / ethanol / 0.08 h / 20 °C

1.2: polyphosphoric acid / 72 h / Reflux

2.1: lithium hydroxide / ethanol; water / 18 h / 20 °C

With sulfuric acid; lithium hydroxide; In ethanol; water;