4-Chloro-2-(4-methoxyphenyl)-6-methylpyrimidine

Base Information

Chemical Name:4-Chloro-2-(4-methoxyphenyl)-6-methylpyrimidine
CAS No.:142245-40-7
Molecular Formula:C12H11ClN2O
Molecular Weight:234.685
Hs Code.:
DSSTox Substance ID:DTXSID90572241
Wikidata:Q82460529
Mol file:142245-40-7.mol

Synonyms:4-chloro-2-(4-methoxyphenyl)-6-methylpyrimidine;142245-40-7;SCHEMBL632828;DTXSID90572241;DBDYYRJBRKKKGY-UHFFFAOYSA-N;MFCD11043810;AKOS009578504;4-chloro-2-(4-methoxy-phenyl)-6-methyl-pyrimidine

Suppliers and Price of 4-Chloro-2-(4-methoxyphenyl)-6-methylpyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-CHLORO-2-(4-METHOXYPHENYL)-6-METHYLPYRIMIDINE 95.00%
5MG
$ 498.10

Total 2 raw suppliers

Chemical Property of 4-Chloro-2-(4-methoxyphenyl)-6-methylpyrimidine

Chemical Property:

PSA：35.01000
LogP:3.11400
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:234.0559907
Heavy Atom Count:16
Complexity:219

Purity/Quality:

99.90% ^*data from raw suppliers

4-CHLORO-2-(4-METHOXYPHENYL)-6-METHYLPYRIMIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NC(=N1)C2=CC=C(C=C2)OC)Cl

Technology Process of 4-Chloro-2-(4-methoxyphenyl)-6-methylpyrimidine

There total 5 articles about 4-Chloro-2-(4-methoxyphenyl)-6-methylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 16858-19-8
2-(4-methoxyphenyl)-6-methylpyrimidin-4-one

: 142245-40-7
4-chloro-2-(4-methoxyphenyl)-6-methylpyrimidine

Guidance literature:: 2-(4-methoxyphenyl)-6-methylpyrimidin-4-one; With trichlorophosphate; at 80 ℃;

With sodium hydroxide; In water;
DOI:10.1016/j.bmc.2012.02.006

Reference yield:

: 16858-19-8
4-hydroxy-2-(4-methoxyphenyl)-6-methyl-pyrimidine

: 142245-40-7
4-chloro-2-(4-methoxyphenyl)-6-methylpyrimidine

Guidance literature:: With trichlorophosphate; In chloroform;

Reference yield:

: 874-90-8
4-methoxybenzonitrile

: 142245-40-7
4-chloro-2-(4-methoxyphenyl)-6-methylpyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium methylate / methanol / 20 °C

1.2: 20 - 60 °C

2.1: trichlorophosphate / 80 °C

With sodium methylate; trichlorophosphate; In methanol;
DOI:10.1016/j.bmc.2012.02.006