Benzenemethanol, 4-[2-(methylamino)ethoxy]-

Base Information

Chemical Name:Benzenemethanol, 4-[2-(methylamino)ethoxy]-
CAS No.:142558-11-0
Molecular Formula:C10H15NO2
Molecular Weight:181.235
Hs Code.:
DSSTox Substance ID:DTXSID20460829
Wikidata:Q82284980

Synonyms:142558-11-0;Benzenemethanol, 4-[2-(methylamino)ethoxy]-;[4-[2-(methylamino)ethoxy]phenyl]methanol;{4-[2-(METHYLAMINO)ETHOXY]PHENYL}METHANOL;[4-(2-methylaminoethoxy)phenyl]methanol;SCHEMBL9124449;DTXSID20460829;AKOS010476857;[4-(2-Methylamino-ethoxy)-phenyl]-methanol;A1-04620

Suppliers and Price of Benzenemethanol, 4-[2-(methylamino)ethoxy]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of Benzenemethanol, 4-[2-(methylamino)ethoxy]-

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:181.110278721
Heavy Atom Count:13
Complexity:122

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CNCCOC1=CC=C(C=C1)CO

Technology Process of Benzenemethanol, 4-[2-(methylamino)ethoxy]-

There total 3 articles about Benzenemethanol, 4-[2-(methylamino)ethoxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 666846-74-8
2-[4-(hydroxymethyl)phenoxy]-N-methylacetamide

: 142558-11-0
4-[2-(methylamino)ethoxypheny]methanol

Guidance literature:: 2-[4-(hydroxymethyl)phenoxy]-N-methylacetamide; With borane-THF; In tetrahydrofuran; at 65 ℃; for 24h;

With hydrogenchloride; In tetrahydrofuran; at 20 ℃; for 1h;

With diethylamine; In tetrahydrofuran; at 20 ℃; for 16h; Further stages.;
DOI:10.1039/b307549d

Reference yield:

: 623-05-2
(4-hydroxyphenyl)methanol

: 142558-11-0
4-[2-(methylamino)ethoxypheny]methanol

Guidance literature:: Multi-step reaction with 3 steps

1.1: 96 percent / K₂CO₃ / dimethylformamide / 2 h / 90 °C

2.1: 100 percent / Amberlyst H-15 / tetrahydrofuran / 48 h / 20 °C

3.1: BH₃*THF / tetrahydrofuran / 24 h / 65 °C

3.2: aq. HCl / tetrahydrofuran / 1 h / 20 °C

3.3: 84 percent / Et₂NH / tetrahydrofuran / 16 h / 20 °C

With borane-THF; Amberlyst H-15; potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1039/b307549d

Reference yield:

: 103258-64-6
ethyl 2-(4-hydroxymethylphenoxy)acetate

: 142558-11-0
4-[2-(methylamino)ethoxypheny]methanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: 100 percent / Amberlyst H-15 / tetrahydrofuran / 48 h / 20 °C

2.1: BH₃*THF / tetrahydrofuran / 24 h / 65 °C

2.2: aq. HCl / tetrahydrofuran / 1 h / 20 °C

2.3: 84 percent / Et₂NH / tetrahydrofuran / 16 h / 20 °C

With borane-THF; Amberlyst H-15; In tetrahydrofuran;
DOI:10.1039/b307549d