2-(diethylamino)-N-(2,3-dimethylphenyl)acetamide

Base Information

• Chemical Name: 2-(diethylamino)-N-(2,3-dimethylphenyl)acetamide
• CAS No.: 142713-08-4
• Molecular Formula: C₁₄H₂₂N₂O
• Molecular Weight: 234.341
• UNII: 6451W1541N
• ChEMBL ID: CHEMBL255832
• Wikidata: Q27263704
• Mol file: 142713-08-4.mol

Synonyms:2-(diethylamino)-N-(2,3-dimethylphenyl)acetamide;142713-08-4;2-Diethylamino-2',3'-acetoxylidide;2',3'-Acetoxylidide, 2-diethylamino-;Acetamide, 2-(diethylamino)-N-(2,3-dimethylphenyl)-;6451W1541N;Lidocaine impurity F [EP];UNII-6451W1541N;Lidocaine hydrochloride impurity F [EP];CHEMBL255832;SCHEMBL2097698;LIDOCAINE IMPURITY F [EP IMPURITY];Q27263704;LIDOCAINE HYDROCHLORIDE IMPURITY F [EP IMPURITY]

Chemical Property of 2-(diethylamino)-N-(2,3-dimethylphenyl)acetamide

Chemical Property:

• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 234.173213330
• Heavy Atom Count: 17
• Complexity: 238

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)CC(=O)NC1=CC=CC(=C1C)C

Technology Process of 2-(diethylamino)-N-(2,3-dimethylphenyl)acetamide

There total 2 articles about 2-(diethylamino)-N-(2,3-dimethylphenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-N-(2, 3-dimethylphenyl)acetamide (2564-07-0) + diethylamine (109-89-7) → 2-(diethylamino)-N-(2,3-dimethyl-phenyl)acetamide (142713-08-4)

Guidance literature:

With benzene;

Reference yield:

2,3-Dimethylaniline (87-59-2) → 2-(diethylamino)-N-(2,3-dimethyl-phenyl)acetamide (142713-08-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium acetate; acetic acid

2: benzene

With sodium acetate; acetic acid; benzene;

upstream raw materials:

2-chloro-N-(2, 3-dimethylphenyl)acetamide

diethylamine

2,3-Dimethylaniline