DIMETHYL 4,5-DIMETHYL-1,4-CYCLOHEXADIENE-1,2-DICARBOXYLATE

Base Information

• Chemical Name: DIMETHYL 4,5-DIMETHYL-1,4-CYCLOHEXADIENE-1,2-DICARBOXYLATE
• CAS No.: 14309-24-1
• Molecular Formula: C12H16O4
• Molecular Weight: 224.257
• Mol file: 14309-24-1.mol

Synonyms:4,5-Dimethyl-1,4-cyclohexadien-1,2-dicarbonsaeure-dimethylester;4,5-dimethyl-cyclohexa-1,4-diene-1,2-dicarboxylic acid dimethyl ester;4,5-Dimethyl-cyclohexa-1,4-dien-1,2-dicarbonsaeure-dimethylester;Dimethyl 3,6-dihydro-4,5-dimethyl phthalate;4,5-Dimethyl-1,4-cyclohexadien-1,4-dicarbonsaeuremethylester;1,4-Cyclohexadiene-1,2-dicarboxylic acid,4,5-dimethyl-,dimethyl ester;Dimethyl 4,5-dimethyl-1,4-cyclohexadiene-1,2-dicarboxylate;11P-115;

Chemical Property of DIMETHYL 4,5-DIMETHYL-1,4-CYCLOHEXADIENE-1,2-DICARBOXYLATE

Chemical Property:

• PSA: 52.60000
• LogP: 1.75920

Purity/Quality:

99.90% ^*data from raw suppliers

DIMETHYL-4,5-DIMETHYL-1,4-CYCLOHEXADIENE-1,2-DICARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIMETHYL 4,5-DIMETHYL-1,4-CYCLOHEXADIENE-1,2-DICARBOXYLATE

There total 10 articles about DIMETHYL 4,5-DIMETHYL-1,4-CYCLOHEXADIENE-1,2-DICARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2,3-dimethyl-buta-1,3-diene (513-81-5) + dimethyl acetylenedicarboxylate (762-42-5) → dimethyl 4,5-dimethylcyclohexa-1,4-diene-1,2-dicarboxylate (14309-24-1)

Guidance literature:

With 1,3-bis[2,4,4,5,7,7,8,8,9,9,9-undecafluoro-2,5-bis(trifluoromethyl)-3,6-dioxanonyl]imidazolium trifluoromethanesulfonate; at 80 ℃; for 2h; Inert atmosphere;

DOI:10.1016/j.jfluchem.2009.04.006

Reference yield: 90.0%

dimethyl 7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate (1829-60-3) + 2,3-dimethyl-buta-1,3-diene (513-81-5) → dimethyl 4,5-dimethylcyclohexa-1,4-diene-1,2-dicarboxylate (14309-24-1) + (1R,4S,4aS,8aR)-dimethyl 6,7-dimethyl-1,4,4a,5,8,8a-hexahydro-1,4-epoxynaphthalene-4a,8a-dicarboxylate

Guidance literature:

With acetic acid; In chloroform; at 25 ℃; for 30h; Temperature; diastereoselective reaction;

DOI:10.1016/j.molstruc.2015.06.012

Reference yield: 70.0%

dimethyl 7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate (1829-60-3) + 2,3-dimethyl-buta-1,3-diene (513-81-5) → dimethyl 4,5-dimethylphthalate (17649-59-1) + dimethyl 4,5-dimethylcyclohexa-1,4-diene-1,2-dicarboxylate (14309-24-1)

Guidance literature:

With acetic acid; In chloroform; at 25 ℃; for 1152h; Reagent/catalyst; Time; Temperature; diastereoselective reaction;

DOI:10.1016/j.molstruc.2015.06.012

upstream raw materials:

2,3-dimethyl-buta-1,3-diene

dimethyl acetylenedicarboxylate

3-isopropenyl-3-methyl-cyclobut-1-ene-1,2-dicarboxylic acid dimethyl ester

dimethyl 7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate

Downstream raw materials:

dimethyl 4,5-dimethylphthalate

4,5-dimethylcyclohexa-1,4-diene-1,2-dicarboxylic acid

1,2-bis(hydroxymethyl)-4,5-dimethylcyclohexa-1,4-diene

4,5-Dimethyl-cyclohexane-1,2-dicarboxylic acid dimethyl ester