2H-1-Benzopyran-6-carboxaldehyde, 3,4-dihydro-2,2-dimethyl-4-oxo-

Base Information

Chemical Name:2H-1-Benzopyran-6-carboxaldehyde, 3,4-dihydro-2,2-dimethyl-4-oxo-
CAS No.:143260-32-6
Molecular Formula:C12H12O3
Molecular Weight:
Hs Code.:
DSSTox Substance ID:DTXSID00458709
Nikkaji Number:J668.267G
Wikidata:Q77563881
Metabolomics Workbench ID:104014

Synonyms:143260-32-6;2H-1-Benzopyran-6-carboxaldehyde, 3,4-dihydro-2,2-dimethyl-4-oxo-;Lactarochromal;DTXSID00458709;2,2-dimethylchroman-4-one-6-carboxaldehyde;F2147-8391;2,2-dimethyl-4-oxo-3,4-dihydro-2H-1-benzopyran-6-carbaldehyde;3,4-Dihydro-2,2-dimethyl-2H-1-benzopyran-4-one-6-carboxaldehyde

Suppliers and Price of 2H-1-Benzopyran-6-carboxaldehyde, 3,4-dihydro-2,2-dimethyl-4-oxo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2H-1-Benzopyran-6-carboxaldehyde, 3,4-dihydro-2,2-dimethyl-4-oxo-

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:204.078644241
Heavy Atom Count:15
Complexity:283

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC(=O)C2=C(O1)C=CC(=C2)C=O)C

Technology Process of 2H-1-Benzopyran-6-carboxaldehyde, 3,4-dihydro-2,2-dimethyl-4-oxo-

There total 1 articles about 2H-1-Benzopyran-6-carboxaldehyde, 3,4-dihydro-2,2-dimethyl-4-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 63678-14-8
2,2,6-trimethyl-4-chromanone

: 67-64-1
acetone

: 65372-54-5
2,2-dimethyl-4-chromanone-6-carboxylic acid

: 143260-32-6
lactarochromal

Guidance literature:: With dipotassium peroxodisulfate; copper(I) sulfate; copper(II) sulfate; In acetonitrile; at 75 - 80 ℃; for 1h; Heating;

Reference yield:

: 143260-32-6
lactarochromal

: 221301-39-9
C,C,C-trifluoro-N-[3-(6-formyl-2,2-dimethyl-4-oxo-chroman-3-ylmethyl)-4-methoxy-phenyl]-methanesulfonamide

Guidance literature:: Multi-step reaction with 6 steps

1: 77 percent / p-TsOH / toluene / Heating

2: 60 percent / (CH₃O)4Si, KF / dimethylformamide / 80 °C

3: 91 percent / H₂ / Pd/C / ethyl acetate / 1551.44 Torr / Ambient temperature

4: TEA / CH₂Cl₂ / 0 °C

5: 5N aq. NaOH / methanol / Ambient temperature

6: 2 N aq. HCl, MeOH / Ambient temperature

With hydrogenchloride; methanol; potassium fluoride; sodium hydroxide; tetramethylorthosilicate; TEA; hydrogen; toluene-4-sulfonic acid; palladium on activated charcoal; In methanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; toluene;
DOI:10.1016/S0960-894X(98)00654-4

Reference yield:

: 143260-32-6
lactarochromal

: N-[3-(6-[1,3]dioxolan-2-yl-2,2-dimethyl-4-oxo-chroman-3-ylmethyl)-4-methoxy-phenyl]-C,C,C-trifluoro-methanesulfonamide

Guidance literature:: Multi-step reaction with 5 steps

1: 77 percent / p-TsOH / toluene / Heating

2: 60 percent / (CH₃O)4Si, KF / dimethylformamide / 80 °C

3: 91 percent / H₂ / Pd/C / ethyl acetate / 1551.44 Torr / Ambient temperature

4: TEA / CH₂Cl₂ / 0 °C

5: 5N aq. NaOH / methanol / Ambient temperature

With potassium fluoride; sodium hydroxide; tetramethylorthosilicate; TEA; hydrogen; toluene-4-sulfonic acid; palladium on activated charcoal; In methanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; toluene;
DOI:10.1016/S0960-894X(98)00654-4