65372-54-5

Usage

Uses

Used in Pharmaceutical Industry:
3,4-Dihydro-2,2-dimethyl-4-oxo-2H-1-benzopyran-6-carboxylic Acid is used as a key intermediate compound for the preparation of chromanone and chromone analogues of diacylhydrazines. These analogues exhibit insecticidal activity, making them valuable for the development of new insecticides to control pests in agriculture and other industries.
Used in Chemical Synthesis:
In the field of chemical synthesis, 3,4-Dihydro-2,2-dimethyl-4-oxo-2H-1-benzopyran-6-carboxylic Acid serves as a versatile building block for the creation of various chemical compounds with potential applications in different industries. Its unique structure allows for further functionalization and modification, enabling the synthesis of a wide range of products with diverse properties and uses.
Used in Insect Control:
3,4-Dihydro-2,2-dimethyl-4-oxo-2H-1-benzopyran-6-carboxylic Acid is used as a starting material for the development of novel insecticides with potential applications in agriculture, horticulture, and other industries. The insecticidal activity of its derived chromanone and chromone analogues of diacylhydrazines makes it a promising candidate for the control of various insect pests, contributing to improved crop yields and reduced reliance on traditional chemical insecticides.

Upstream product

• 2345-34-8 4-acetyloxy-benzoic acid 
• 123-75-1 pyrrolidine 
• 16357-40-7 3-acetyl-4-hydroxybenzoic acid 
• 99-96-7 4-hydroxy-benzoic acid 
• 1450-72-2 5-methyl-2-hydroxyacetophenone 
• 63678-14-8 2,2,6-trimethyl-4-chromanone 
• 67-64-1 acetone 
• 57009-53-7 ethyl 3-acetyl-4-hydroxybenzoate 
• 933055-06-2 ethyl 2,2-dimethyl-4-chromanone-6-carboxylate 

Relevant academic research and scientific papers

Synthesis and insecticidal activity of chromanone and chromone analogues of diacylhydrazines

Diacylhydrazine derivatives have been identified as one of the most important insect growth regulators. A variety of diacylhydrazine derivatives were designed and synthesized in recent years due to their unique action mechanism, simple structure, and environmental benign character. This paper describes the molecular design, synthesis, and insecticidal activities of a series of chromanone and chromone analogues of diacylhydrazine derivatives. The preliminary bioassay showed that some of the chromanone analogues exhibited good insecticidal activity against Mythima separata at the dosage of 500 mg L-1. The present work demonstrated that replacement of the chroman ring of ANS-118, a commercial insecticide, with chromanone moiety could result in new compounds with high potent insecticidal activity.

Sulfonamide-substituted chromans, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising them

Sulfonamide-substituted chromans, processes for their preparation, their use as a medicament or a diagnostic, and medicament comprising them Chromans of the formula I and of the formula 1a having the meanings R(A), R(B), R(C) and R(1) to R(8) indicated in the claims are outstandingly suitable for preparing a medicament for blocking the K+channel which is opened by cyclic adenosine monophosphate (cAMP); and further for preparing a medicament for inhibiting gastric acid secretion; for the treatment of ulcers of the stomach and of the intestinal region, in particular of the duodenum, for the treatment of reflux esophagitis, for the treatment of diarrheal illnesses, for the treatment and prevention of all types of arrhythmias including ventricular and supraventricular arrhythmias, and for the control of reentry arrhythmias and for the prevention of sudden heart death as a result of ventricular fibrillation.

A short and facile synthesis of lactarochromal and the corresponding acid

Lactamrochromal (1), a metabolite of Lactarius deliciosus and the corresponding acid (2), also a natural product from Chrysothamnus viscidiflorus have been synthesized starting from p-cresol.

Titanium mediated reductive amination on solid support: Extending the utility of the 4-hydroxy-thiophenol linker

The solid supported synthesis of a library of 8,448 benzopyrans was accomplished using the 4-hydroxythiophenol react and release linker. Reductive aminations were performed in parallel using a Ti(OiPr)4/Na(OAc)3BH reducing system. This reduction was performed without cleavage of resin bound substrates from the nucleophile sensitive linker.