Benzoic acid, 2-[3,3,4,4,5,5,5-heptafluoro-2-(2-methoxy-2-oxoethylidene)-1-(triphenyl phosphoranylidene)pentyl]-, ethyl ester, (Z)-

Base Information

• Chemical Name: Benzoic acid, 2-[3,3,4,4,5,5,5-heptafluoro-2-(2-methoxy-2-oxoethylidene)-1-(triphenyl phosphoranylidene)pentyl]-, ethyl ester, (Z)-
• CAS No.: 143366-20-5
• Molecular Formula: C₃₅H₂₈F₇O₄P
• Molecular Weight: 676.568
• Mol file: 143366-20-5.mol

Synonyms:

Chemical Property of Benzoic acid, 2-[3,3,4,4,5,5,5-heptafluoro-2-(2-methoxy-2-oxoethylidene)-1-(triphenyl phosphoranylidene)pentyl]-, ethyl ester, (Z)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoic acid, 2-[3,3,4,4,5,5,5-heptafluoro-2-(2-methoxy-2-oxoethylidene)-1-(triphenyl phosphoranylidene)pentyl]-, ethyl ester, (Z)-

There total 3 articles about Benzoic acid, 2-[3,3,4,4,5,5,5-heptafluoro-2-(2-methoxy-2-oxoethylidene)-1-(triphenyl phosphoranylidene)pentyl]-, ethyl ester, (Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(o-ethoxycarbonylbenzyl)triphenylphosphonium bromide (59636-00-9) + methyl 4,4,5,5,6,6,6-heptafluorohex-2-ynoate (70577-96-7) → 2-[3,3,4,4,5,5,5-Heptafluoro-2-[1-methoxycarbonyl-meth-(E)-ylidene]-1-(triphenyl-λ5-phosphanylidene)-pentyl]-benzoic acid ethyl ester (143366-20-5,143366-24-9) + 2-{(Z)-3,3,4,4,5,5,5-Heptafluoro-2-[methoxycarbonyl-(triphenyl-λ5-phosphanylidene)-methyl]-pent-1-enyl}-benzoic acid ethyl ester (143366-13-6,143366-15-8)

Guidance literature:

With potassium carbonate; In 1,2-dimethoxyethane; at 15 - 25 ℃; for 48h; Yield given. Title compound not separated from byproducts;

DOI:10.1055/s-1992-26182

Reference yield:

triphenylphosphine (603-35-0) → 2-[3,3,4,4,5,5,5-Heptafluoro-2-[1-methoxycarbonyl-meth-(E)-ylidene]-1-(triphenyl-λ5-phosphanylidene)-pentyl]-benzoic acid ethyl ester (143366-20-5,143366-24-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / dimethylformamide / 12 h / 50 - 60 °C

2: K₂CO₃ / 1,2-dimethoxy-ethane / 48 h / 15 - 25 °C

With potassium carbonate; In 1,2-dimethoxyethane; N,N-dimethyl-formamide;

DOI:10.1055/s-1992-26182

Reference yield:

2-ethoxycarbonylbenzyl bromide (7115-91-5) → 2-[3,3,4,4,5,5,5-Heptafluoro-2-[1-methoxycarbonyl-meth-(E)-ylidene]-1-(triphenyl-λ5-phosphanylidene)-pentyl]-benzoic acid ethyl ester (143366-20-5,143366-24-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / dimethylformamide / 12 h / 50 - 60 °C

2: K₂CO₃ / 1,2-dimethoxy-ethane / 48 h / 15 - 25 °C

With potassium carbonate; In 1,2-dimethoxyethane; N,N-dimethyl-formamide;

DOI:10.1055/s-1992-26182

upstream raw materials:

(o-ethoxycarbonylbenzyl)triphenylphosphonium bromide

methyl 4,4,5,5,6,6,6-heptafluorohex-2-ynoate

triphenylphosphine

2-ethoxycarbonylbenzyl bromide

Refernces