N-(2-Nitrobenzylidene)aniline

Base Information

• Chemical Name: N-(2-Nitrobenzylidene)aniline
• CAS No.: 17064-77-6
• Molecular Formula: C13H10 N2 O2
• Molecular Weight: 226.235
• European Community (EC) Number: 241-126-8
• NSC Number: 148947
• DSSTox Substance ID: DTXSID901281234
• Nikkaji Number: J2.506.943I,J104.653E
• Mol file: 17064-77-6.mol

Synonyms:N-(2-Nitrobenzylidene)aniline;1-(2-nitrophenyl)-N-phenylmethanimine;17064-77-6;Benzenamine, N-[(2-nitrophenyl)methylene]-;Aniline, N-(o-nitrobenzylidene)-;N-(o-Nitrobenzylidene)aniline;EINECS 241-126-8;Benzenamine, N-((2-nitrophenyl)methylene)-;NSC148947;2-Nitrobenzal-anilin;SCHEMBL4727410;SCHEMBL10478287;DTXSID901281234;N-[(E)-2-Nitrobenzylidene]aniline;AKOS024328945;(E)-N-(2-nitrobenzylidene)benzenamine;NSC 148947;NSC-148947;1-(2-nitrophenyl)-N-phenyl-methanimine;N-[(2-Nitrophenyl)methylene]benzenamine;N-[(E)-(2-Nitrophenyl)methylidene]aniline;FT-0656081;N-[(2-NITROPHENYL)METHYLIDENE]ANILINE;N-[(E)-(2-Nitrophenyl)methylidene]aniline #;A811222;Z54890899

Chemical Property of N-(2-Nitrobenzylidene)aniline

Chemical Property:

• Vapor Pressure: 9.75E-06mmHg at 25°C
• Boiling Point: 383.4°Cat760mmHg
• Flash Point: 185.7°C
• PSA: 58.18000
• Density: 1.16g/cm³
• LogP: 3.86860
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 226.074227566
• Heavy Atom Count: 17
• Complexity: 280

Purity/Quality:

99% ^*data from raw suppliers

1-(2-NITROPHENYL)-N-PHENYLMETHANIMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)N=CC2=CC=CC=C2[N+](=O)[O-]

Technology Process of N-(2-Nitrobenzylidene)aniline

There total 4 articles about N-(2-Nitrobenzylidene)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

aniline (62-53-3) + 2-nitro-benzaldehyde (552-89-6) → N-(2-nitrobenzylidene)aniline (17064-77-6)

Guidance literature:

In neat (no solvent); for 0.166667h; Time; Irradiation; Green chemistry;

DOI:10.14233/ajchem.2013.14382

Reference yield: 35.0%

2-Nitrobenzyl alcohol (612-25-9) + aniline (62-53-3) → N-(2-nitrobenzylidene)aniline (17064-77-6)

Guidance literature:

With nanosized zeolite Beta; air; at 135 ℃; for 24h; Green chemistry;

DOI:10.1039/c3gc41345d

Reference yield:

N-(2-nitrobenzylidene)-4-nitroaniline (17064-86-7) + aniline (62-53-3) → N-(2-nitrobenzylidene)aniline (17064-77-6)

Guidance literature:

With 1-butyl-2,3-(trimethylene)imidazolium bis(trifluoromethanesulfonyl)imide; at 20 ℃; for 1h;

DOI:10.1039/c0ob01094d

upstream raw materials:

aniline

2-nitro-benzaldehyde

N-(2-nitrobenzylidene)-4-nitroaniline

2-Nitrobenzyl alcohol

Downstream raw materials:

(E)-N-phenyl-2-(phenyldiazenyl)benzamide

3-(2-nitrophenyl)-2-carboxy-2-propenoic acid

2-nitrocinnamic acid

2-(2-nitrophenyl)-2-phenylaminoacetonitrile

Refernces

• 1、 Aguilera-Perdomo, Jacobo David,Cortés-Benítez, Francisco,Cortés-Gines, Miguel,Del Angel, Kevin Samael Olascoaga,Pérez-Villanueva, Jaime,Palacios-Espinosa, Juan Francisco,Quintana-Salazar, Edgar A.,Rodríguez-Villar, Karen,Soria-Arteche, Olivia,Yépez-Mulia, Lilián. "Synthesis, antiprotozoal activity, and cheminformatic analysis of 2-phenyl-2h-indazole derivatives". . . Retrieved 2021/05/28.
• 2、 Cortés-Benítez, Francisco,González-Sánchez, Ignacio,Leyte-Lugo, Martha,Macías-Jiménez, Ana Perla,Matadamas-Martínez, Félix,Pérez-Koldenkova, Vadim,Pérez-Villanueva, Jaime,Palacios-Espinosa, Juan Francisco,Rodríguez-Villar, Karen,Romero-Velásquez, Ariana,Soria-Arteche, Olivia,Yépez-Mulia, Lilián. "Synthesis and cytotoxic activity of combretastatin a-4 and 2,3-diphenyl-2h-indazole hybrids". . . Retrieved 2021/08/31.