Octahydro-9a-methyl-2H-quinolizine

Base Information

• Chemical Name: Octahydro-9a-methyl-2H-quinolizine
• CAS No.: 4939-43-9
• Molecular Formula: C10H19N
• Molecular Weight: 0
• Mol file: 4939-43-9.mol

Synonyms:9a-methyl-octahydro-quinolizin;10-Methyl-chinolizidin;10-Methylchinolizidin;9a-Methyl-octahydro-chinolizin;6-Methyl-1-aza-bicyclo<4.4.0>decan;9a-Methyl-octahydro-quinolizine;

Chemical Property of Octahydro-9a-methyl-2H-quinolizine

Chemical Property:

• Boiling Point: 70 - 73 °C (12 mmHg)
• PSA: 3.24000
• LogP: 2.35280

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Octahydro-9a-methyl-2H-quinolizine

There total 6 articles about Octahydro-9a-methyl-2H-quinolizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2,3,4,6,7,8,9-octahydroquinolizin-5-ium perchlorate → 10-Methyl-chinolizidin (4939-43-9)

Guidance literature:

With methyl magnesium iodide; diethyl ether;

DOI:10.1021/ja01607a064

Reference yield:

6-cyano-1-azabicyclo<4.4.0>decane (23805-76-7) → 10-Methyl-chinolizidin (4939-43-9)

Guidance literature:

With diethyl ether; methylmagnesium bromide;

DOI:10.1021/ja01590a062

Reference yield:

quinolizidine (493-10-7) → 10-Methyl-chinolizidin (4939-43-9)

Guidance literature:

Multi-step reaction with 3 steps

1: mercury (II)-acetate; aqueous acetic acid

2: aqueous perchloric acid; ethanol

3: methyl magnesium iodide; diethyl ether

With methyl magnesium iodide; perchloric acid; diethyl ether; ethanol; mercury(II) diacetate; acetic acid;

DOI:10.1021/ja01607a064

upstream raw materials:

methyl magnesium iodide

diethyl ether

6-cyano-1-azabicyclo<4.4.0>decane

quinolizidine

Refernces