2-Hydroxy-2,2-diphenylacetamide

Base Information

Chemical Name:2-Hydroxy-2,2-diphenylacetamide
CAS No.:4746-87-6
Molecular Formula:C14H13NO2
Molecular Weight:227.263
Hs Code.:2924299090
European Community (EC) Number:225-262-5
NSC Number:46049
UNII:7TP6A7L0FC
DSSTox Substance ID:DTXSID60197147
Nikkaji Number:J236.725D
Wikidata:Q83070111
Mol file:4746-87-6.mol

Synonyms:Benzilamide;2-Hydroxy-2,2-diphenylacetamide;4746-87-6;2,2-Diphenylglycolamide;EINECS 225-262-5;NSC 46049;Benzeneacetamide, .alpha.-hydroxy-.alpha.-phenyl-;BRN 2214258;7TP6A7L0FC;alpha-Hydroxy-alpha-phenylbenzeneacetamide;alpha,alpha-Diphenyl-alpha-hydroxyacetamide;.alpha.,.alpha.-Diphenyl-.alpha.-hydroxyacetamide;Benzeneacetamide, alpha-hydroxy-alpha-phenyl- (9CI);NSC-46049;Benzeneacetamide, alpha-hydroxy-alpha-phenyl-;NSC46049;UNII-7TP6A7L0FC;SCHEMBL366365;DTXSID60197147;STK102994;AKOS005397294;Benzeneethanamide, a-hydroxy-a-phenyl-;SB79845;NCGC00335735-01;LS-32436;CS-0359243;FT-0635425;AB01328448-02;.ALPHA.-HYDROXY-.ALPHA.-PHENYLBENZENEACETAMIDE

Suppliers and Price of 2-Hydroxy-2,2-diphenylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Benzylamide
500mg
$ 265.00

American Custom Chemicals Corporation
BENZILAMIDE 98.00%
2.5KG
$ 6710.00

Total 8 raw suppliers

Chemical Property of 2-Hydroxy-2,2-diphenylacetamide

Chemical Property:

Vapor Pressure:2.55E-08mmHg at 25°C
Boiling Point:434.5°Cat760mmHg
Flash Point:216.6°C
PSA：63.32000
Density:1.231g/cm³
LogP:2.10810
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:227.094628657
Heavy Atom Count:17
Complexity:247

Purity/Quality:

99% ^*data from raw suppliers

Benzylamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C2=CC=CC=C2)(C(=O)N)O
Uses Benzylamide is a useful reagent for doing Hofmann rearrangement of α,α-disubstituted α-hydroxy amides.

Technology Process of 2-Hydroxy-2,2-diphenylacetamide

There total 15 articles about 2-Hydroxy-2,2-diphenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 4746-48-9
2-hydroxy-2,2-diphenylacetonitrile

: 4746-87-6
benzilamide

Guidance literature:: With silver trifluoromethanesulfonate; C₃₃H₃₃ClO₇P₃Pt⁽¹⁺⁾*CF₃O₃S^(1-); In tetrahydrofuran; water; at 23 ℃; Catalytic behavior;
DOI:10.1021/acscatal.1c02254