2-Bromo-3,4-dihydroxy-5-methoxybenzoic acid

Base Information

Chemical Name:2-Bromo-3,4-dihydroxy-5-methoxybenzoic acid
CAS No.:143883-73-2
Molecular Formula:C8H7BrO5
Molecular Weight:263.045
Hs Code.:
DSSTox Substance ID:DTXSID10566642
Wikidata:Q82452348
Mol file:143883-73-2.mol

Synonyms:143883-73-2;2-Bromo-3,4-dihydroxy-5-methoxybenzoic acid;DTXSID10566642

Suppliers and Price of 2-Bromo-3,4-dihydroxy-5-methoxybenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-Bromo-3,4-dihydroxy-5-methoxybenzoic acid

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:261.94769
Heavy Atom Count:14
Complexity:222

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=C(C(=C1)C(=O)O)Br)O)O

Technology Process of 2-Bromo-3,4-dihydroxy-5-methoxybenzoic acid

There total 2 articles about 2-Bromo-3,4-dihydroxy-5-methoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 3934-84-7
3,4-dihydroxy-5-methoxybenzoic acid

: 143883-73-2
2-bromo-5-O-methyl gallic acid

Guidance literature:: With bromine; 1,1-dibromomethane; In 1,2-dichloro-ethane; for 5h;
DOI:10.1016/0223-5234(92)90148-T

Reference yield:

: 149-91-7
3,4,5-trihydroxybenzoic acid

: 143883-73-2
2-bromo-5-O-methyl gallic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) aq. NaOH, 5percent borax, 2.) 20percent NaOH / 1.) RT, 3 h, 2.) reflux, 1 h

2: 74 percent / Br₂, CH₂Br₂ / 1,2-dichloro-ethane / 5 h

With borax; sodium hydroxide; bromine; 1,1-dibromomethane; In 1,2-dichloro-ethane;
DOI:10.1016/0223-5234(92)90148-T