Ethanimidoyl iodide, 2,2,2-trifluoro-N-(4-nitrophenyl)-

Base Information

• Chemical Name: Ethanimidoyl iodide, 2,2,2-trifluoro-N-(4-nitrophenyl)-
• CAS No.: 144008-08-2
• Molecular Formula: C8H4F3IN2O2
• Molecular Weight: 344.032
• Mol file: 144008-08-2.mol

Synonyms:

Chemical Property of Ethanimidoyl iodide, 2,2,2-trifluoro-N-(4-nitrophenyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanimidoyl iodide, 2,2,2-trifluoro-N-(4-nitrophenyl)-

There total 2 articles about Ethanimidoyl iodide, 2,2,2-trifluoro-N-(4-nitrophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(4-nitrophenyl)-2,2,2-trifluoroacetimidoyl chloride (145372-31-2) → 2,2,2-Trifluoro-N-(4-nitro-phenyl)-acetimidoyl iodide (144008-08-2)

Guidance literature:

With sodium iodide; In acetone;

DOI:10.1016/S0040-4039(00)74253-5

Reference yield:

4-nitro-aniline (100-01-6,104810-17-5) → 2,2,2-Trifluoro-N-(4-nitro-phenyl)-acetimidoyl iodide (144008-08-2)

Guidance literature:

Multi-step reaction with 2 steps

1: triphenylphosphine, TEA, CCl₄ / Heating

2: NaI / acetone

With tetrachloromethane; TEA; triphenylphosphine; sodium iodide; In acetone;

DOI:10.1016/S0040-4039(00)74253-5

Reference yield: 27%

ethanol (64-17-5) + carbon monoxide (201230-82-2) + 2,2,2-Trifluoro-N-(4-nitro-phenyl)-acetimidoyl iodide (144008-08-2) → 3,3,3-Trifluoro-2-[(E)-4-nitro-phenylimino]-propionic acid ethyl ester (144008-14-0)

Guidance literature:

With potassium carbonate; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In toluene; for 6.5h; under 760 Torr; Ambient temperature;

DOI:10.1016/S0040-4039(00)74253-5

upstream raw materials:

N-(4-nitrophenyl)-2,2,2-trifluoroacetimidoyl chloride

4-nitro-aniline

Downstream raw materials:

3,3,3-Trifluoro-2-[(E)-4-nitro-phenylimino]-propionic acid ethyl ester

Refernces