2-Propanone, 1-phenyl-3-(phenylmethoxy)-

Base Information

• Chemical Name: 2-Propanone, 1-phenyl-3-(phenylmethoxy)-
• CAS No.: 144018-68-8
• Molecular Formula: C16H16O2
• Molecular Weight: 240.302
• DSSTox Substance ID: DTXSID90455484
• Nikkaji Number: J601.031H
• Mol file: 144018-68-8.mol

Synonyms:2-Propanone, 1-phenyl-3-(phenylmethoxy)-;144018-68-8;SCHEMBL23258691;DTXSID90455484;1-(Benzyloxy)-3-phenyl-2-propanone;AKOS011305215

Chemical Property of 2-Propanone, 1-phenyl-3-(phenylmethoxy)-

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 240.115029749
• Heavy Atom Count: 18
• Complexity: 238

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CC(=O)COCC2=CC=CC=C2

Technology Process of 2-Propanone, 1-phenyl-3-(phenylmethoxy)-

There total 8 articles about 2-Propanone, 1-phenyl-3-(phenylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

potassium α-benzyloxymethyltrifluoroborate + phenylacetyl chloride (103-80-0) → 3-phenyl-1-(phenylmethoxy)-2-propanone (144018-68-8)

Guidance literature:

With (1,2-dimethoxyethane)dichloronickel(II); (R)-4-(tert-butyl)-2-(pyridin-2-yl)-4,5-dihydrooxazole; Ir(dF(CF₃)ppy)2(bpy)PF₆; caesium carbonate; In tetrahydrofuran; at 24 ℃; for 24h; Inert atmosphere; Irradiation; Sealed tube;

DOI:10.1021/acs.orglett.5b03705

Reference yield: 40.0%

3,3-bis(phenylmethyl)-1,2-dioxetane (40814-69-5) → 3-phenyl-1-(phenylmethoxy)-2-propanone (144018-68-8) + 1,3-Diphenylpropanone (102-04-5)

Guidance literature:

at 25 ℃; for 18h;

DOI:10.1021/ja00049a009

Reference yield: 36.0%

1,4-dioxene (543-75-9) + 3,3-bis(phenylmethyl)-1,2-dioxetane (40814-69-5) → 3-phenyl-1-(phenylmethoxy)-2-propanone (144018-68-8) + cis-3,3-dibenzyl-2,5,7,10-tetraoxabicyclo<4.4.0>decane (144018-69-9) + 1,3-Diphenylpropanone (102-04-5)

Guidance literature:

In dichloromethane; for 18h; Yields of byproduct given;

DOI:10.1021/ja00049a009

upstream raw materials:

2-(benzyloxy)acetamide

benzylmagnesium chloride

1,4-dioxene

3,3-bis(phenylmethyl)-1,2-dioxetane

Downstream raw materials:

3-(benzyloxy)-1-phenylpropan-2-ol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 144018-68-8 2-Propanone, 1-phenyl-3-(phenylmethoxy)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send