1,4-Bis(2-nitrophenoxy)butane

Base Information

• Chemical Name: 1,4-Bis(2-nitrophenoxy)butane
• CAS No.: 14467-64-2
• Molecular Formula: C16H16N2O6
• Molecular Weight: 332.313
• European Community (EC) Number: 653-229-9
• Mol file: 14467-64-2.mol

Synonyms:1,4-bis(2-nitrophenoxy)butane;1-nitro-2-[4-(2-nitrophenoxy)butoxy]benzene;1,4-bis(nitrophenoxy) butane;AKOS024334090;SR-01000207133;SR-01000207133-1

Chemical Property of 1,4-Bis(2-nitrophenoxy)butane

Chemical Property:

• PSA: 110.10000
• LogP: 4.78740
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 332.10083623
• Heavy Atom Count: 24
• Complexity: 370

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,4-BIS(2-NITROPHENOXY)BUTANE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)[N+](=O)[O-])OCCCCOC2=CC=CC=C2[N+](=O)[O-]

Technology Process of 1,4-Bis(2-nitrophenoxy)butane

There total 4 articles about 1,4-Bis(2-nitrophenoxy)butane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,4-dibromo-butane (110-52-1) + 2-hydroxynitrobenzene (88-75-5,78813-12-4) → 1,6-bis(2-nitrophenyl)-1,6-dioxahexane (14467-64-2)

Guidance literature:

With 18-crown-6 ether; potassium carbonate; In N,N-dimethyl-formamide; at 140 ℃; for 5h;

Reference yield: 80.0%

1,4-dibromo-butane (110-52-1) + 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) → 1,6-bis(2-nitrophenyl)-1,6-dioxahexane (14467-64-2)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 115 ℃;

DOI:10.1021/acs.cgd.0c01742

Reference yield: 60.0%

1,4-dibromo-butane (110-52-1) + sodium o-nitrophenate (824-39-5) → 1,6-bis(2-nitrophenyl)-1,6-dioxahexane (14467-64-2)

Guidance literature:

In N,N-dimethyl-formamide; for 2h; Heating;

upstream raw materials:

1,4-dibromo-butane

sodium o-nitrophenate

2-hydroxynitrobenzene

4-nitro-phenol

Downstream raw materials:

C₃₀H₂₆Cl₂N₂O₄

17-(Toluene-4-sulfonyl)-2,7-dioxa-14,17,20-triaza-tricyclo[19.4.0.0^8,13]pentacosa-1⁽²⁵⁾,8⁽¹³⁾,9,11,21,23-hexaene-15,19-dione

17-(Toluene-4-sulfonyl)-2,7-dioxa-14,17,20-triaza-tricyclo[19.4.0.0^8,13]pentacosa-1⁽²⁵⁾,8⁽¹³⁾,9,11,21,23-hexaene

1,4-bis(o-aminophenoxy)butane-N,N,N',N'-tetraacetic acid