16-(Benzyloxy)-16-Oxohexadecanoic Acid

Base Information

• Chemical Name: 16-(Benzyloxy)-16-Oxohexadecanoic Acid
• CAS No.: 146004-98-0
• Molecular Formula: C23H36O4
• Molecular Weight: 376.536
• Mol file: 146004-98-0.mol

Synonyms:

Chemical Property of 16-(Benzyloxy)-16-Oxohexadecanoic Acid

Chemical Property:

• Boiling Point: 505.8±23.0 °C(Predicted)
• PKA: 4.78±0.10(Predicted)
• PSA: 0.00000
• Density: 1.023±0.06 g/cm3(Predicted)
• LogP: 0.00000
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

16-Oxo-16-PhenylmethoxyhexadecanoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 16-(Benzyloxy)-16-Oxohexadecanoic Acid

There total 10 articles about 16-(Benzyloxy)-16-Oxohexadecanoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

dibenzyl hexadecanedioate → 16-(benzyloxy)-16-oxohexadecanoic acid (146004-98-0)

Guidance literature:

dibenzyl hexadecanedioate; With potassium carbonate; In methanol; at 70 ℃; for 2h;

With hydrogenchloride; In methanol; water; pH=1-2; Reagent/catalyst; Solvent; Temperature;

Reference yield: 55.6%

thapsic acid (505-54-4) + benzyl bromide (100-39-0) → 16-(benzyloxy)-16-oxohexadecanoic acid (146004-98-0)

Guidance literature:

With sodium carbonate; In 2-methyltetrahydrofuran; water; at 75 ℃; for 22h;

Reference yield: 50.0%

thapsic acid (505-54-4) + benzyl chloride (100-44-7) → 16-(benzyloxy)-16-oxohexadecanoic acid (146004-98-0)

Guidance literature:

With potassium carbonate; In tetrahydrofuran; water; at 80 ℃; for 40h;

upstream raw materials:

benzyl alcohol

thapsic acid

benzyl formate

benzyl bromide

Downstream raw materials:

1,14-tetradecanedicarboxylic acid monochloride monobenzyl ester

benzyl 16-((2,5-dioxopyrrolidin-1-yl)oxy)-16-oxohexadecanoate

C₅₂H₈₄NO₈⁽¹⁺⁾*I^(1-)

C₅₁H₈₁NO₈