Butanoic acid, 2-[methyl[(phenylmethoxy)carbonyl]amino]-, (2S)-

Base Information

Chemical Name:Butanoic acid, 2-[methyl[(phenylmethoxy)carbonyl]amino]-, (2S)-
CAS No.:146087-16-3
Molecular Formula:C13H17NO4
Molecular Weight:251.27800
Hs Code.:

Synonyms:2-(benzyloxycarbonyl-methyl-amino)-butyric acid;N-Cbz-(S)-2-(methylamino)butyric acid;

Suppliers and Price of Butanoic acid, 2-[methyl[(phenylmethoxy)carbonyl]amino]-, (2S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Activate Scientific
N-Cbz-(S)-2-(methylamino)butyric acid 95% ee
5 g
$ 897.00

Activate Scientific
N-Cbz-(S)-2-(methylamino)butyric acid 95% ee
1 g
$ 328.00

Acrotein
N-Cbz-(S)-2-(methylamino)butyricacid 97%
1g
$ 220.00

Total 5 raw suppliers

Chemical Property of Butanoic acid, 2-[methyl[(phenylmethoxy)carbonyl]amino]-, (2S)-

Chemical Property:

PSA：66.84000
LogP:2.11820

Purity/Quality:

99% ^*data from raw suppliers

N-Cbz-(S)-2-(methylamino)butyric acid 95% ee ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Butanoic acid, 2-[methyl[(phenylmethoxy)carbonyl]amino]-, (2S)-

There total 2 articles about Butanoic acid, 2-[methyl[(phenylmethoxy)carbonyl]amino]-, (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 42918-86-5,1145-79-5,2900-20-1,20395-87-3
(S)-2-(((benzyloxy)carbonyl)amino)butanoic acid

: 146087-16-3
(2S)-2-(methyl{[(phenylmethyl)oxy]carbonyl}amino)butanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: CSA / toluene / Heating

2: Et₃SiH; CF₃COOH / CH₂Cl₂

With triethylsilane; trifluoroacetic acid; camphor-10-sulfonic acid; In dichloromethane; toluene;
DOI:10.1002/hlca.200690235

Reference yield:

: 95656-94-3
phenylmethyl (4S)-5-oxo-4-ethyl-1,3-oxazolidine-3-carboxylate

: 146087-16-3
(2S)-2-(methyl{[(phenylmethyl)oxy]carbonyl}amino)butanoic acid

Guidance literature:: With triethylsilane; trifluoroacetic acid; In dichloromethane;
DOI:10.1002/hlca.200690235

Reference yield: 80.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 146087-16-3
(2S)-2-(methyl{[(phenylmethyl)oxy]carbonyl}amino)butanoic acid

: 922705-67-7
phenylmethyl [(1S)-3-diazo-1-ethyl-2-oxopropyl]methylcarbamate

Guidance literature:: (2S)-2-(methyl{[(phenylmethyl)oxy]carbonyl}amino)butanoic acid; With 4-methyl-morpholine; chloroformic acid ethyl ester; In tetrahydrofuran; at -15 ℃; for 0.25h;

diazomethane; In tetrahydrofuran; dichloromethane; at -15 - 20 ℃;
DOI:10.1002/hlca.200690235