1,3-Dimethyl-4-(phenylsulfonyl)-2,4-dihydropyrrolo[3,4-b]indole

Base Information

Chemical Name:1,3-Dimethyl-4-(phenylsulfonyl)-2,4-dihydropyrrolo[3,4-b]indole
CAS No.:146253-26-1
Molecular Formula:C18H16N2O2S
Molecular Weight:324.403
Hs Code.:
DSSTox Substance ID:DTXSID50573830
Nikkaji Number:J1.662.688K
Wikidata:Q82462665
Mol file:146253-26-1.mol

Synonyms:146253-26-1;1,3-Dimethyl-4-(phenylsulfonyl)-2,4-dihydropyrrolo[3,4-b]indole;DTXSID50573830;4-(Benzenesulfonyl)-1,3-dimethyl-2,4-dihydropyrrolo[3,4-b]indole

Suppliers and Price of 1,3-Dimethyl-4-(phenylsulfonyl)-2,4-dihydropyrrolo[3,4-b]indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1,3-Dimethyl-4-(phenylsulfonyl)-2,4-dihydropyrrolo[3,4-b]indole

Chemical Property:

XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:324.09324893
Heavy Atom Count:23
Complexity:538

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C3=CC=CC=C3N(C2=C(N1)C)S(=O)(=O)C4=CC=CC=C4

Technology Process of 1,3-Dimethyl-4-(phenylsulfonyl)-2,4-dihydropyrrolo[3,4-b]indole

There total 5 articles about 1,3-Dimethyl-4-(phenylsulfonyl)-2,4-dihydropyrrolo[3,4-b]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 146253-25-0
1-(phenylsulfonyl)-2-(1-azidoethyl)-3-indolyl methyl ketone

: 146253-26-1
4-(phenylsulfonyl)-1,3-dimethyl-2,4-dihydropyrrolo<3,4-b>indole

Guidance literature:: With triphenylphosphine; In tetrahydrofuran; for 8h; Ambient temperature;
DOI:10.1016/S0040-4020(01)88360-5

Reference yield:

: 17422-23-0
1-(2-ethyl-1H-indol-3-yl)-ethan-1-one

: 146253-26-1
4-(phenylsulfonyl)-1,3-dimethyl-2,4-dihydropyrrolo<3,4-b>indole

Guidance literature:: Multi-step reaction with 4 steps

1: 1) KH, 2) imidazole / 1) dimethoxyethane, room temperature, 1 h, 2) dimethoxyethane, room temperature, 15 h

2: 90 percent / NBS, dibenzoyl peroxide / CCl₄ / 4 h / Heating

3: 95 percent / NaN₃ / tetrahydrofuran; H₂O / 4 h / Ambient temperature

4: 94 percent / triphenylphosphine / tetrahydrofuran / 8 h / Ambient temperature

With 1H-imidazole; N-Bromosuccinimide; sodium azide; potassium hydride; triphenylphosphine; dibenzoyl peroxide; In tetrahydrofuran; tetrachloromethane; water;
DOI:10.1016/S0040-4020(01)88360-5

Reference yield:

: 146253-24-9
1-(phenylsulfonyl)-2-(1-bromoethyl)-3-indolyl methyl ketone

: 146253-26-1
4-(phenylsulfonyl)-1,3-dimethyl-2,4-dihydropyrrolo<3,4-b>indole

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / NaN₃ / tetrahydrofuran; H₂O / 4 h / Ambient temperature

2: 94 percent / triphenylphosphine / tetrahydrofuran / 8 h / Ambient temperature

With sodium azide; triphenylphosphine; In tetrahydrofuran; water;
DOI:10.1016/S0040-4020(01)88360-5