1,4-Dioxaspiro[4.5]dec-7-ene

Base Information

• Chemical Name: 1,4-Dioxaspiro[4.5]dec-7-ene
• CAS No.: 7092-24-2
• Molecular Formula: C8H12O2
• Molecular Weight: 140.182
• DSSTox Substance ID: DTXSID80221150
• Nikkaji Number: J381.384C
• Wikidata: Q83098783
• Mol file: 7092-24-2.mol

Synonyms:1,4-Dioxaspiro[4.5]dec-7-ene;7092-24-2;1,4-Dioxaspiro(4.5)dec-7-ene;SCHEMBL4383265;DTXSID80221150;1,4-dioxaspiro[4.5]dec-7-en;AHIKUUYIVLCZGL-UHFFFAOYSA-N;3-cyclohexen-1-one ethylene ketal;3-Cyclohexene-1-One Ethylene Ketal;AB89974;EN300-134045

Chemical Property of 1,4-Dioxaspiro[4.5]dec-7-ene

Chemical Property:

• Vapor Pressure: 0.351mmHg at 25°C
• Boiling Point: 205.8°Cat760mmHg
• Flash Point: 74.9°C
• Density: 1.08g/cm³
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 140.083729621
• Heavy Atom Count: 10
• Complexity: 145

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2(CC=C1)OCCO2

Technology Process of 1,4-Dioxaspiro[4.5]dec-7-ene

There total 16 articles about 1,4-Dioxaspiro[4.5]dec-7-ene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-methoxycyclohexa-1,4-diene (2886-59-1) + ethylene glycol (107-21-1) → 1,4-dioxaspiro<4.5>dec-7-ene (7092-24-2)

Guidance literature:

toluene-4-sulfonic acid; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1021/ol026739q

Reference yield: 100.0%

(7S,8S)-7,8-Dibromo-1,4-dioxa-spiro[4.5]decane → 1,4-dioxaspiro<4.5>dec-7-ene (7092-24-2)

Guidance literature:

With 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; ethylmagnesium bromide; In tetrahydrofuran; at 0 ℃;

DOI:10.1016/0040-4039(95)01988-T

Reference yield: 99.0%

2,2,7,7-tetramethyl-3,6-dioxa-2,7-disilaoctane (7381-30-8) + cyclohex-3-enone (4096-34-8) → 1,4-dioxaspiro<4.5>dec-7-ene (7092-24-2)

Guidance literature:

trimethylsilyl trifluoromethanesulfonate; In dichloromethane; 1.) -78 degC, 3h 2.)-20 degC, 0.2h;

DOI:10.1016/S0040-4039(00)74575-8

upstream raw materials:

4-(1,4-dioxaspiro<4.5>dec-7-en-8-yl)morpholine

cyclohexenone

2,2,7,7-tetramethyl-3,6-dioxa-2,7-disilaoctane

cyclohex-3-enone

Downstream raw materials:

cyclohex-3-enone

8-hydroxy-1,4-dioxa-spiro[4,5]dec-6-ene

7-hydroxy-1,4-dioxa-spiro[4,5]dec-6-ene

1-methyl-1,2,3,3a,4,7a-hexahydro-5H-inden-5-one