Benzene, 1-methoxy-4-[(3-methyl-2-methylenebutoxy)methyl]-

Base Information

• Chemical Name: Benzene, 1-methoxy-4-[(3-methyl-2-methylenebutoxy)methyl]-
• CAS No.: 148675-55-2
• Molecular Formula: C14H20O2
• Molecular Weight: 220.312
• DSSTox Substance ID: DTXSID00454307
• Nikkaji Number: J819.955H
• Mol file: 148675-55-2.mol

Synonyms:148675-55-2;Benzene, 1-methoxy-4-[(3-methyl-2-methylenebutoxy)methyl]-;DTXSID00454307;(2-Isopropylallyl)(4-methoxybenzyl) ether

Chemical Property of Benzene, 1-methoxy-4-[(3-methyl-2-methylenebutoxy)methyl]-

Chemical Property:

• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 220.146329876
• Heavy Atom Count: 16
• Complexity: 203

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)C(=C)COCC1=CC=C(C=C1)OC

Technology Process of Benzene, 1-methoxy-4-[(3-methyl-2-methylenebutoxy)methyl]-

There total 1 articles about Benzene, 1-methoxy-4-[(3-methyl-2-methylenebutoxy)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-isopropylallyl alcohol (26903-66-2) + p-methoxybenzyl chloride (824-94-2) → 1-(4-methoxybenzyloxy)-2-(2-propyl)-2-propene (148675-55-2)

Guidance literature:

With sodium hydride; Yield given. Multistep reaction; 1) THF, DMF, 0 deg C, 30 min, 2) THF, 120 min;

DOI:10.1016/S0040-4020(01)86347-X

Reference yield: 75.0%

glyoxylic acid ethyl ester (924-44-7) + 1-(4-methoxybenzyloxy)-2-(2-propyl)-2-propene (148675-55-2) → 2-Hydroxy-4-(4-methoxy-benzyloxymethyl)-5-methyl-hex-4-enoic acid ethyl ester

Guidance literature:

With titanium(IV) dichlorodiisopropylate; In dichloromethane; at -20 ℃; for 48h;

DOI:10.1016/S0040-4020(01)86347-X

Reference yield: 74.0%

1-(4-methoxybenzyloxy)-2-(2-propyl)-2-propene (148675-55-2) → 4-(4-methoxyphenyl)-2-(2-propyl)butanal (189366-70-9)

Guidance literature:

Zeolite β; In dichloromethane; Ambient temperature;

DOI:10.1039/a608020k

upstream raw materials:

2-isopropylallyl alcohol

p-methoxybenzyl chloride

Downstream raw materials:

(S)-2-Hydroxy-4-(4-methoxy-benzyloxymethyl)-5-methyl-hex-4-enoic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

4-(4-methoxyphenyl)-2-(2-propyl)butanal

2-Hydroxy-4-(4-methoxy-benzyloxymethyl)-5-methyl-hex-4-enoic acid cyclohexyl ester

2-Hydroxy-4-(4-methoxy-benzyloxymethyl)-5-methyl-hex-4-enoic acid 1,2-dimethyl-propyl ester