2-Benzyl-N-methoxybenzamide

Base Information

Chemical Name:2-Benzyl-N-methoxybenzamide
CAS No.:148991-82-6
Molecular Formula:C15H15NO2
Molecular Weight:241.29
Hs Code.:
DSSTox Substance ID:DTXSID90576421
Nikkaji Number:J1.841.605K
Wikidata:Q82466106
Mol file:148991-82-6.mol

Synonyms:2-Benzyl-N-methoxybenzamide;148991-82-6;DTXSID90576421;AKOS030580255;NCGC00327832-01;AB01323482-02;Z193289858

Suppliers and Price of 2-Benzyl-N-methoxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-Benzyl-N-methoxybenzamide

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:241.110278721
Heavy Atom Count:18
Complexity:261

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CONC(=O)C1=CC=CC=C1CC2=CC=CC=C2

Technology Process of 2-Benzyl-N-methoxybenzamide

There total 12 articles about 2-Benzyl-N-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 55810-66-7
2-(benzyl)benzoyl chloride

: 593-56-6
N-methoxylamine hydrochloride

: 148991-82-6
2-benzyl-N-methoxybenzamide

Guidance literature:: With water; potassium carbonate; In ethyl acetate; at 20 ℃;
DOI:10.1002/chem.201804229

Reference yield:

: 612-35-1
2-Benzylbenzoic acid

: 148991-82-6
2-benzyl-N-methoxybenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: (COCl)2, DMF / CH₂Cl₂ / 16 h / Ambient temperature

2: Et₃N / CH₂Cl₂ / 2 h / 0 °C

With oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1021/jo00066a014

Reference yield:

: 6962-60-3
2-benzyl-benzoic acid methyl ester

: 593-56-6
N-methoxylamine hydrochloride

: 148991-82-6
2-benzyl-N-methoxybenzamide

Guidance literature:: 2-benzyl-benzoic acid methyl ester; With potassium hydroxide; In ethanol; water; Reflux;

N-methoxylamine hydrochloride; With dmap; In dichloromethane; for 0.5h;

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃;
DOI:10.1021/acs.joc.7b00106