55810-66-7Relevant academic research and scientific papers
Eosin Y as a Redox Catalyst and Photosensitizer for Sequential Benzylic C?H Amination and Oxidation
Yan, Dong-Mei,Zhao, Quan-Qing,Rao, Li,Chen, Jia-Rong,Xiao, Wen-Jing
, p. 16895 - 16901 (2018/10/26)
A new synergistic multicatalytic activation mode of eosin Y has been discovered by exploiting the redox potential of its ground state and excited state. This catalytic strategy proves to be an enabling tool for visible-light-driven sequential benzylic C?H amination and oxidation of o-benzyl-N-methoxyl-benzamides when using Selectfluor as a hydrogen atom transfer (HAT) reagent and O2 as oxidant. Efficient synthesis of a range of diversely functionalized 3-hydroxyisoindolinones can thus be achieved with good yields and selectivity at mild reaction conditions. Preliminary mechanistic studies and DFT calculations suggest that eosin Y works as a redox catalyst and photosensitizer.
Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them
-
, (2008/06/13)
Compounds of formula I, wherein, R1, R2, R3 and R5 have the meanings defined in the specification,G2 represents a chain -(CH2)z(W)y-, in which W has various meanings including C=O, and up to two of the methylene segments in the chain (CH2)zare optionally replaced by -NH- and one segment is optionally replaced by -O- or -(C=NR40)-, and the chain is optionally unsaturated and optionally substituted, and, A is a 5- or 6-membered ring or a bicyclic or tricyclic fused ring system, A being optionally substituted by various substituents,possess useful pharmacological properties, in particular as cardiotonics. Also described are processes for the preparation of compounds of formula I, pharmaceutical compositions containing them and methods of treatment involving their use.
