5-(o-Methoxyphenoxy)-4,6-dichloro-2-(4-pyridyl)pyrimidine

Base Information

Chemical Name:5-(o-Methoxyphenoxy)-4,6-dichloro-2-(4-pyridyl)pyrimidine
CAS No.:150727-72-3
Molecular Formula:C16H11Cl2N3O2
Molecular Weight:348.18300
Hs Code.:
DSSTox Substance ID:DTXSID30457780
Wikidata:Q82280775
Mol file:150727-72-3.mol

Synonyms:150727-72-3;5-(o-Methoxyphenoxy)-4,6-dichloro-2-(4-pyridyl)pyrimidine;4,6-DICHLORO-5-(2-METHOXYPHENOXY)-2-(PYRIDIN-4-YL)PYRIMIDINE;4,6-dichloro-5-(2-methoxyphenoxy)-2-pyridin-4-ylpyrimidine;Pyrimidine, 4,6-dichloro-5-(2-methoxyphenoxy)-2-(4-pyridinyl)-;4,6-dichloro-5-(o-methoxyphenoxy)-2-(4-pyridyl)-pyrimidine;4,6-dichloro-5-(2-methoxyphenoxy)-2-(4-pyridyl)-pyrimidine;SCHEMBL4071996;DTXSID30457780;BCP14514;CS-M2682;AKOS037650318;CS-14627;FT-0728861;C12595;A1-12046;5-(o-methoxyphenoxy)-4,6-dichloro-2-(4-pyridyl)-pyrimidine

Suppliers and Price of 5-(o-Methoxyphenoxy)-4,6-dichloro-2-(4-pyridyl)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4,6-Dichloro-5-(o-methoxyphenoxy)-2-(4-pyridyl)-pyrimidine 95%
2.500g
$ 2310.00

Chemenu
5-(o-Methoxyphenoxy)-4,6-dichloro-2-(4-pyridyl)pyrimidine 95%+
1g
$ 688.00

Chemenu
5-(o-Methoxyphenoxy)-4,6-dichloro-2-(4-pyridyl)pyrimidine 95%+
100mg
$ 221.00

Chemenu
5-(o-Methoxyphenoxy)-4,6-dichloro-2-(4-pyridyl)pyrimidine 95%+
250mg
$ 211.00

A1 Biochem Labs
4,6-Dichloro-5-(o-methoxyphenoxy)-2-(4-pyridyl)-pyrimidine 95%
2.5 g
$ 1050.00

Total 10 raw suppliers

Chemical Property of 5-(o-Methoxyphenoxy)-4,6-dichloro-2-(4-pyridyl)pyrimidine

Chemical Property:

Boiling Point:372.7±42.0 °C(Predicted)
PKA:0.21±0.10(Predicted)
PSA：57.13000
Density:1.376±0.06 g/cm3(Predicted)
LogP:4.64630
XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:347.0228320
Heavy Atom Count:23
Complexity:359

Purity/Quality:

98%min ^*data from raw suppliers

4,6-Dichloro-5-(o-methoxyphenoxy)-2-(4-pyridyl)-pyrimidine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1OC2=C(N=C(N=C2Cl)C3=CC=NC=C3)Cl

Technology Process of 5-(o-Methoxyphenoxy)-4,6-dichloro-2-(4-pyridyl)pyrimidine

There total 7 articles about 5-(o-Methoxyphenoxy)-4,6-dichloro-2-(4-pyridyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 150728-08-8
5-(o-methoxyphenoxy)-4,6-dihydroxy-2-(pyridin-4-yl)-pyrimidine

: 150727-72-3
4,6-dichloro-5-(o-methoxyphenoxy)-2-(pyridin-4-yl)-pyrimidine

Guidance literature:: With N,N-dimethyl-aniline; trichlorophosphate; at 120 ℃;
DOI:10.1016/S0960-894X(02)01084-3

Reference yield:

: 20730-58-9
2-(2-Methoxyphenoxy)propanedioic acid diethyl ester

: 150727-72-3
4,6-dichloro-5-(o-methoxyphenoxy)-2-(pyridin-4-yl)-pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: NaOMe / methanol / 18 h / 20 °C

2: POCl₃; PhNMe₂ / 120 °C

With sodium methylate; N,N-dimethyl-aniline; trichlorophosphate; In methanol;
DOI:10.1016/S0960-894X(02)01084-3

Reference yield:

: 6345-27-3,42518-06-9,61875-64-7
4-amidinopyridine hydrochloride

: 150727-72-3
4,6-dichloro-5-(o-methoxyphenoxy)-2-(pyridin-4-yl)-pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: NaOMe / methanol / 18 h / 20 °C

2: POCl₃; PhNMe₂ / 120 °C

With sodium methylate; N,N-dimethyl-aniline; trichlorophosphate; In methanol;
DOI:10.1016/S0960-894X(02)01084-3