(2S)-4-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-[[(phenylmethoxy)carbonyl]amino]butanoic acid

Base Information

Chemical Name:(2S)-4-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-[[(phenylmethoxy)carbonyl]amino]butanoic acid
CAS No.:151132-82-0
Molecular Formula:C27H26N2O6
Molecular Weight:460.52200
Hs Code.:
Mol file:151132-82-0.mol

Synonyms:(2S)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-2-(phenylmethoxymethylamino)butanoic acid;

Suppliers and Price of (2S)-4-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-[[(phenylmethoxy)carbonyl]amino]butanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(((benzyloxy)methyl)amino)butanoic acid 95+%
1g
$ 370.00

Matrix Scientific
(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(((benzyloxy)methyl)amino)butanoic acid 95+%
250mg
$ 167.00

Crysdot
(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(((benzyloxy)methyl)amino)butanoicacid 95+%
1g
$ 96.00

Crysdot
(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(((benzyloxy)methyl)amino)butanoicacid 95+%
5g
$ 448.00

ChemPep
Z-Dab(Fmoc)-OH
25g
$ 750.00

ChemPep
Z-Dab(Fmoc)-OH
5g
$ 295.00

Biosynth Carbosynth
Z-L-Dab(Fmoc)-OH
2 g
$ 273.70

Biosynth Carbosynth
Z-L-Dab(Fmoc)-OH
1 g
$ 171.10

Biosynth Carbosynth
Z-L-Dab(Fmoc)-OH
250 mg
$ 60.00

Biosynth Carbosynth
Z-L-Dab(Fmoc)-OH
500 mg
$ 105.00

Total 13 raw suppliers

Chemical Property of (2S)-4-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-[[(phenylmethoxy)carbonyl]amino]butanoic acid

Chemical Property:

Boiling Point:739.8±60.0 °C(Predicted)
PKA:3.86±0.10(Predicted)
PSA：96.89000
Density:1.299
LogP:4.91410
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(((benzyloxy)methyl)amino)butanoic acid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2S)-4-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-[[(phenylmethoxy)carbonyl]amino]butanoic acid

There total 7 articles about (2S)-4-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-[[(phenylmethoxy)carbonyl]amino]butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 28920-43-6
(fluorenylmethoxy)carbonyl chloride

: 62234-40-6
(2S)-2-{[(benzyloxy)carbonyl]amino}-4-(dimethylamino)butanoic acid

: 151132-82-0,369611-58-5
Nα-Z-Nγ-Fmoc-L-2,4-diaminobutyric acid

Guidance literature:: With sodium hydrogencarbonate; In tetrahydrofuran; water; at 20 ℃; for 3h;
DOI:10.1016/S0968-0896(01)00228-0

Reference yield:

: 13907-82-9,2650-67-1
N²-benzyloxycarbonyl-L-glutamine methyl ester

: 151132-82-0,369611-58-5
Nα-Z-Nγ-Fmoc-L-2,4-diaminobutyric acid

Guidance literature:: Multi-step reaction with 4 steps

1: benzene / acetonitrile; H₂O / 144 h / Ambient temperature

2: DIEA / dioxane / 3 h / Ambient temperature

3: 78 percent / 1 N NaOH / methanol / 2 h / Ambient temperature

4: 1) TFA, 2) aq. Na₂CO₃ / 2) dioxane, 4 deg C, 2 h

With sodium hydroxide; bis-(trifluoroacetoxy)-iodo-benzene; sodium carbonate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In 1,4-dioxane; methanol; water; acetonitrile;
DOI:10.1016/S0223-5234(98)80006-8

Reference yield:

: 182618-33-3
(S)-4-Amino-2-benzyloxycarbonylamino-butyric acid methyl ester

: 151132-82-0,369611-58-5
Nα-Z-Nγ-Fmoc-L-2,4-diaminobutyric acid

Guidance literature:: Multi-step reaction with 3 steps

1: DIEA / dioxane / 3 h / Ambient temperature

2: 78 percent / 1 N NaOH / methanol / 2 h / Ambient temperature

3: 1) TFA, 2) aq. Na₂CO₃ / 2) dioxane, 4 deg C, 2 h

With sodium hydroxide; sodium carbonate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In 1,4-dioxane; methanol;
DOI:10.1016/S0223-5234(98)80006-8