3,3-Diphenyl-3H-pyrano[3,2-f]quinoline

Base Information

• Chemical Name: 3,3-Diphenyl-3H-pyrano[3,2-f]quinoline
• CAS No.: 152365-47-4
• Molecular Formula: C₂₄H₁₇NO
• Molecular Weight: 335.405
• DSSTox Substance ID: DTXSID10572460
• Nikkaji Number: J849.576I
• Wikidata: Q82460821
• Mol file: 152365-47-4.mol

Synonyms:3,3-Diphenyl-3H-pyrano[3,2-f]quinoline;152365-47-4;SCHEMBL13220117;DTXSID10572460;8,8-diphenyl-[8H]-pyrano[3,2-f] quinoline

Chemical Property of 3,3-Diphenyl-3H-pyrano[3,2-f]quinoline

Chemical Property:

• XLogP3: 5.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 335.131014166
• Heavy Atom Count: 26
• Complexity: 484

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2(C=CC3=C(O2)C=CC4=C3C=CC=N4)C5=CC=CC=C5

Technology Process of 3,3-Diphenyl-3H-pyrano[3,2-f]quinoline

There total 2 articles about 3,3-Diphenyl-3H-pyrano[3,2-f]quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-hydroxyquinoline (580-16-5) + 3,3-diphenyl-2-propenal (1210-39-5) → 3,3-diphenyl-3H-pyrano[3,2-f]quinoline (152365-47-4)

Guidance literature:

With titanium(IV) tetraethanolate; Yield given. Multistep reaction; 1.) toluene, reflux, 2.) reflux, 3 h;

DOI:10.1080/10587259408037791

Reference yield:

5-[3,3-Diphenyl-prop-2-en-(Z)-ylidene]-5H-quinolin-6-one → 3,3-diphenyl-3H-pyrano[3,2-f]quinoline (152365-47-4)

Guidance literature:

In toluene; at 25 ℃; Kinetics; Flash photolysis;

DOI:10.1007/BF02503478

Reference yield:

trimethylsilyl cyanide (7677-24-9) + chloroacetone (78-95-5) + 3,3-diphenyl-3H-pyrano[3,2-f]quinoline (152365-47-4) → C28H20N2OS

Guidance literature:

3,3-diphenyl-3H-pyrano[3,2-f]quinoline; With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃;

trimethylsilyl cyanide; With benzoyl chloride; In dichloromethane; Reflux;

chloroacetone; Further stages;

DOI:10.1016/j.dyepig.2019.108167

upstream raw materials:

6-hydroxyquinoline

3,3-diphenyl-2-propenal