2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, 3-methylbutyl ester

Base Information

• Chemical Name: 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, 3-methylbutyl ester
• CAS No.: 152368-04-2
• Molecular Formula: C14H18O4
• Molecular Weight: 0.00000
• Mol file: 152368-04-2.mol

Synonyms:KF-31327;2H-Imidazo(4,5-g)quinazoline-2-thione,3-ethyl-1,3-dihydro-8-(((2-(4-(hydroxymethyl)-1-piperidinyl)phenyl)methyl)amino)-,hydrochloride (1:2);3-Ethyl-8-(2-(4-hydroxymethylpiperidino)benzylamino)-2,3-dihydro-1H-imidazo(4,5-g)quinazoline-2-thione dihydrochloride;2H-Imidazo(4,5-g)quinazoline-2-thione,3-ethyl-1,3-dihydro-8-(((2-(4-(hydroxymethyl)-1-piperidinyl)phenyl)methyl)amino)-,dihydrochloride;Thioquinapiperifil dihydrochloride;

Chemical Property of 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, 3-methylbutyl ester

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, 3-methylbutyl ester

There total 3 articles about 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, 3-methylbutyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

i-Amyl alcohol (123-51-3) + caffeic acid (331-39-5,501-16-6) → (E)-isopentyl 3-(3,4-dihydroxyphenyl)acrylate (152368-04-2)

Guidance literature:

With sulfuric acid; at 142 ℃; for 0.0833333h; Microwave irradiation;

DOI:10.1002/ddr.21015

Reference yield: 69.0%

i-Amyl alcohol (123-51-3) + caffeic acid (331-39-5,501-16-6) → isopentyl caffeate (152368-04-2)

Guidance literature:

Microwave irradiation;

DOI:10.1016/j.bmcl.2012.08.038

Reference yield:

i-Amyl alcohol (123-51-3) + (E)-3-(3,4-dihydroxyphenyl)acryloyl chloride (77201-71-9) → (E)-isopentyl 3-(3,4-dihydroxyphenyl)acrylate (152368-04-2)

Guidance literature:

at 90 ℃;

DOI:10.1021/jf060899p

upstream raw materials:

i-Amyl alcohol

caffeic acid

(E)-3-(3,4-dihydroxyphenyl)acryloyl chloride

caffeic acid

Refernces

• 1、 Boudreau, Luc H.,Lassalle-Claux, Grégoire,Cormier, Marc,Blanchard, Sébastien,Doucet, Marco S.,Surette, Marc E.,Touaibia, Mohamed. "New Hydroxycinnamic Acid Esters as Novel 5-Lipoxygenase Inhibitors That Affect Leukotriene Biosynthesis". . . Retrieved 2017/07/06.
• 2、 Bhullar, Khushwant S.,Lassalle-Claux, Grégoire,Touaibia, Mohamed,Vasantha Rupasinghe. "Antihypertensive effect of caffeic acid and its analogs through dual renin-angiotensin-aldosterone system inhibition". . p. 125 - 132. Retrieved 2014/04/17.