3-Phenyl-1,2,5-oxadiazole

Base Information

• Chemical Name: 3-Phenyl-1,2,5-oxadiazole
• CAS No.: 10349-06-1
• Molecular Formula: C8H6 N2 O
• Molecular Weight: 146.148
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID50145874
• Nikkaji Number: J602.416E
• Wikidata: Q83010558
• Mol file: 10349-06-1.mol

Synonyms:3-Phenyl-1,2,5-oxadiazole;Phenylfurazan;10349-06-1;3-Phenylfurazan;Phenyl-1,2,5-oxdiazol;SCHEMBL1520375;3-Phenyl-1,2,5-oxadiazole #;DTXSID50145874;CHJJHGSNNPEDNJ-UHFFFAOYSA-N;AC2765;MFCD01648512;AKOS024352287;SY129105;A921414

Chemical Property of 3-Phenyl-1,2,5-oxadiazole

Chemical Property:

• Vapor Pressure: 0.021mmHg at 25°C
• Boiling Point: 259.4°C at 760 mmHg
• Flash Point: 115.1°C
• PSA: 38.92000
• Density: 1.179g/cm³
• LogP: 1.73660
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 146.048012819
• Heavy Atom Count: 11
• Complexity: 123

Purity/Quality:

97% ^*data from raw suppliers

3-PHENYLFURAZAN 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NON=C2

Technology Process of 3-Phenyl-1,2,5-oxadiazole

There total 17 articles about 3-Phenyl-1,2,5-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

phenylglyoxime (4589-97-3) → 3-phenylfurazan (10349-06-1)

Guidance literature:

With succinic acid anhydride; at 105 - 110 ℃;

DOI:10.1007/BF00513282

Reference yield:

3-phenyl-furazan 5-oxide (7707-64-4) + hydrogen iodide (10034-85-2) → 3-phenylfurazan (10349-06-1) + 2-Aminoacetophenone (613-89-8)

Guidance literature:

Reference yield:

phenyl-glyoxal-bis-(O-propionyl oxime ) + furan-2,3,5(4H)-trione pyridine (1:1) → 3-phenylfurazan (10349-06-1) + 2-(hydroxyimino)-2-phenylacetonitrile (825-52-5)

Guidance literature:

α-phenylglyoxime dipropionate;

upstream raw materials:

anti-phenylglyoxime

phenyl-glyoxal-bis-(O-acetyl oxime )

phenylglyoxal-(1Z,2E)-dioxime

benzoyl chloride

Downstream raw materials:

(4-Phenyl-furazan-3-yl)-acetic acid methyl ester

dimethyl cis-but-2-ene-1,4-dioate

3-(4-Nitro-phenyl)-furazan

3-(2,4-Dinitro-phenyl)-furazan