1,3-Benzenediamine,N-propyl-(9CI)

Base Information

• Chemical Name: 1,3-Benzenediamine,N-propyl-(9CI)
• CAS No.: 155525-49-8
• Molecular Formula: C9H14N2
• Molecular Weight: 150.224
• Mol file: 155525-49-8.mol

Synonyms:1,3-Benzenediamine,N-propyl;3-propylaminoaniline;1-N-propylbenzene-1,3-diamine;

Chemical Property of 1,3-Benzenediamine,N-propyl-(9CI)

Chemical Property:

• PSA: 38.05000
• LogP: 2.74490

Purity/Quality:

99.90% ^*data from raw suppliers

1-N-propylbenzene-1,3-diamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-Benzenediamine,N-propyl-(9CI)

There total 3 articles about 1,3-Benzenediamine,N-propyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

3-nitro-N-propylbenzeneamine (87035-66-3) → 3-propylaminoaniline (155525-49-8)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; for 2h;

DOI:10.1016/j.tet.2011.12.038

Reference yield: 93.0%

propylamine (107-10-8,42939-71-9) + m-Bromoaniline (591-19-5) → 3-propylaminoaniline (155525-49-8)

Guidance literature:

With copper(I) oxide; In 1-methyl-pyrrolidin-2-one; at 110 ℃; for 24h; Inert atmosphere;

DOI:10.1039/b823407h

Reference yield:

3-nitro-aniline (99-09-2) → 3-propylaminoaniline (155525-49-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C

1.2: 96 h / 60 °C

2.1: palladium 10% on activated carbon; hydrogen / methanol / 2 h

With palladium 10% on activated carbon; hydrogen; sodium hydride; In methanol; N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2011.12.038

upstream raw materials:

propylamine

m-Bromoaniline

3-nitro-N-propylbenzeneamine

3-nitro-aniline

Downstream raw materials:

C₁₇H₃₀N₂O₃

C₅₇H₇₆N₈O₇

C₃₁H₃₈N₆O₉

C₃₇H₅₀N₆O₉

Refernces

• 1、 Xu, Hanhui,Wolf, Christian. "Copper catalyzed coupling of aryl chlorides, bromides and iodides with amines and amides". supporting information; experimental part. p. 1715 - 1717. Retrieved 2009/08/08.