3-Bromo-2-hydroxypropanoic acid

Base Information

• Chemical Name: 3-Bromo-2-hydroxypropanoic acid
• CAS No.: 32777-03-0
• Molecular Formula: C3H5 Br O3
• Molecular Weight: 168.97
• Hs Code.: 2918199090
• European Community (EC) Number: 824-175-5
• NSC Number: 159402
• UNII: 24IBD46Q2E
• Wikidata: Q27253853
• Mol file: 32777-03-0.mol

Synonyms:3-bromolactate;3-bromolactic acid

Chemical Property of 3-Bromo-2-hydroxypropanoic acid

Chemical Property:

• Vapor Pressure: 4.13E-05mmHg at 25°C
• Boiling Point: 314°Cat760mmHg
• Flash Point: 143.7°C
• PSA: 57.53000
• Density: 2.017g/cm³
• LogP: -0.17320
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 167.94221
• Heavy Atom Count: 7
• Complexity: 72.6

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(=O)O)O)Br

Technology Process of 3-Bromo-2-hydroxypropanoic acid

There total 6 articles about 3-Bromo-2-hydroxypropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3?bromopyruvate (68-38-2) → (R,S)-3-bromo-2-hydroxypropanoic acid (32777-03-0)

Guidance literature:

With 1,6-di-o-phosphonohex-2-ulofuranose; piperazine*HCl buffer; NADH; at 25 ℃; Rate constant; pH 6.0, reaction in the presence of L-lactate dehydrogenase from Bacillus stearothermophilus (BSLDH Q₁₀₂R) or other enzymes;

DOI:10.1021/ja00038a016

Reference yield:

→ (R,S)-3-bromo-2-hydroxypropanoic acid (32777-03-0)

Guidance literature:

With nitric acid; l-β-bromo-lactic acid; entsteht in teilweise racemisiertem Zustand;

Reference yield:

→ (R,S)-3-bromo-2-hydroxypropanoic acid (32777-03-0)

Guidance literature:

With MORPHIN; l-β-bromo-lactic acid;

upstream raw materials:

glycidic acid

3?bromopyruvate

nitric acid

1,2-Epoxy-3-bromopropane

Downstream raw materials:

(+)-2,3-epoxy-propionic acid ; potassium-salt

Refernces