2-ethyl-5-methoxy-1H-indole

Base Information

Chemical Name:2-ethyl-5-methoxy-1H-indole
CAS No.:163688-10-6
Molecular Formula:C11H13NO
Molecular Weight:175.23
Hs Code.:
DSSTox Substance ID:DTXSID70443667
Wikidata:Q82261567
Mol file:163688-10-6.mol

Synonyms:2-ethyl-5-methoxy-1H-indole;163688-10-6;1H-Indole, 2-ethyl-5-methoxy-;2-ETHYL-5-METHOXYINDOLE;SCHEMBL2157095;DTXSID70443667;UIEHVKCFXAZDCJ-UHFFFAOYSA-N;AKOS006284787;A810500

Suppliers and Price of 2-ethyl-5-methoxy-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-ETHYL-5-M ETHOXY-1H-INDOLE 95.00%
5MG
$ 502.40

AccelPharmtech
2-ethyl-5-methoxy-1H-Indole 97.00%
25G
$ 7320.00

Total 1 raw suppliers

Chemical Property of 2-ethyl-5-methoxy-1H-indole

Chemical Property:

PSA：25.02000
LogP:2.73890
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:175.099714038
Heavy Atom Count:13
Complexity:172

Purity/Quality:

97% ^*data from raw suppliers

2-ETHYL-5-M ETHOXY-1H-INDOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC1=CC2=C(N1)C=CC(=C2)OC

Technology Process of 2-ethyl-5-methoxy-1H-indole

There total 4 articles about 2-ethyl-5-methoxy-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 163688-09-3
1-[2-(tert-butoxycarbonylamino)-5-methoxyphenyl]-2-butanone

: 163688-10-6
2-ethyl-5-methoxy-1H-indole

Guidance literature:: With trifluoroacetic acid; In dichloromethane; for 72h;
DOI:10.1021/jm960485v

Reference yield: 58.0%

: 163688-10-6
2-ethyl-5-methoxy-1H-indole

Guidance literature:

Reference yield:

: 129822-42-0
N-(tert-butoxycarbonyl)-4-methoxy-2-methylaniline

: 163688-10-6
2-ethyl-5-methoxy-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1: s-BuLi / tetrahydrofuran / -40 - 20 °C

2: CF₃CO₂H / CH₂Cl₂

With sec.-butyllithium; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmcl.2005.06.067