2-Methyl-4-methoxyaniline tert-butyl carbamate

Base Information

• Chemical Name: 2-Methyl-4-methoxyaniline tert-butyl carbamate
• CAS No.: 129822-42-0
• Molecular Formula: C13H19NO3
• Molecular Weight: 237.299
• Hs Code.: 2924299090
• DSSTox Substance ID: DTXSID60698588
• Mol file: 129822-42-0.mol

Synonyms:2-METHYL-4-METHOXYANILINE TERT-BUTYL CARBAMATE;DTXSID60698588;tert-Butyl carbamate--4-methoxy-2-methylaniline (1/1)

Chemical Property of 2-Methyl-4-methoxyaniline tert-butyl carbamate

Chemical Property:

• PSA: 47.56000
• LogP: 3.42360
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 254.16304257
• Heavy Atom Count: 18
• Complexity: 199

Purity/Quality:

99% ^*data from raw suppliers

tert-Butyl4-methoxy-2-methylphenylcarbamate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CC(=C1)OC)N.CC(C)(C)OC(=O)N

Technology Process of 2-Methyl-4-methoxyaniline tert-butyl carbamate

There total 1 articles about 2-Methyl-4-methoxyaniline tert-butyl carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

di-tert-butyl dicarbonate (24424-99-5) + 2-methyl-4-methoxyaniline (102-50-1) → N-(tert-butoxycarbonyl)-4-methoxy-2-methylaniline (129822-42-0)

Guidance literature:

at 20 ℃; Inert atmosphere; Sonication;

DOI:10.1002/anie.201511149

Reference yield: 95.0%

methanol (67-56-1) + N-(tert-butoxycarbonyl)-4-methoxy-2-methylaniline (129822-42-0) → N-(tert-butoxycarbonyl)-2-methyl-p-benzoquinone imine dimethyl acetal (260391-79-5)

Guidance literature:

With [bis(acetoxy)iodo]benzene; triethylamine; at 20 ℃; for 1h;

DOI:10.1039/c2ob25089f

Reference yield: 81.0%

methanol (67-56-1) + N-(tert-butoxycarbonyl)-4-methoxy-2-methylaniline (129822-42-0) → 4,4-dimethoxy-2-methylcyclohexane-2,5-dien-1-one (57197-11-2)

Guidance literature:

With [bis(acetoxy)iodo]benzene; silica gel; triethylamine; at 20 ℃; for 4h;

DOI:10.1039/c2ob25089f

upstream raw materials:

di-tert-butyl dicarbonate

2-methyl-4-methoxyaniline

Downstream raw materials:

(2-tert-Butoxycarbonylamino-5-methoxy-phenyl)-acetic acid

[4-Methoxy-2-(2-oxo-hexyl)-phenyl]-carbamic acid tert-butyl ester

[2-(6-Chloro-2-oxo-hexyl)-4-methoxy-phenyl]-carbamic acid tert-butyl ester

[2-(5-Chloro-2-oxo-pentyl)-4-methoxy-phenyl]-carbamic acid tert-butyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 129822-42-0 (4-METHOXY-2-METHYL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER

Send

Send

Metric Ton KG G Pound L ML

Send

Send