8-Hydroxydodecanoic acid

Base Information

• Chemical Name: 8-Hydroxydodecanoic acid
• CAS No.: 16899-09-5
• Molecular Formula: C12H24O3
• Molecular Weight: 216.321
• ChEMBL ID: CHEMBL4277376
• DSSTox Substance ID: DTXSID20560515
• Nikkaji Number: J262.043J
• Mol file: 16899-09-5.mol

Synonyms:8-hydroxydodecanoic acid;16899-09-5;8-hydroxylauric acid;Dodecanoic acid, 8-hydroxy-;8-hydroxy-dodecanoic acid;SCHEMBL1882579;CHEMBL4277376;DTXSID20560515;CHEBI:167567;G64620

Chemical Property of 8-Hydroxydodecanoic acid

Chemical Property:

• XLogP3: 3.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 10
• Exact Mass: 216.17254462
• Heavy Atom Count: 15
• Complexity: 157

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCC(CCCCCCC(=O)O)O

Technology Process of 8-Hydroxydodecanoic acid

There total 3 articles about 8-Hydroxydodecanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

lauric acid (143-07-7) → 12-hydroxydodecanoic acid (505-95-3) + 10-hydroxydodecanoic acid + 8-hydroxylauric acid (16899-09-5)

Guidance literature:

With P₄₅₀ BMP enzyme; dihydrogen peroxide; In water; Further Variations:; Reagents; Product distribution;

DOI:10.1002/anie.200351434

Reference yield:

lauric acid (143-07-7) → 9-hydroxydodecanoic acid (68490-89-1) + 7-Hydroxydodecanoic acid (70393-62-3) + 10-hydroxydodecanoic acid + 8-hydroxylauric acid (16899-09-5)

Guidance literature:

With cytochrome P₄₅₀ BM-3 enzyme mutant 9-10A-F₈₇A; Enzymatic reaction;

Reference yield:

Sodium laurate (629-25-4) → 9-hydroxydodecanoic acid (68490-89-1) + 7-Hydroxydodecanoic acid (70393-62-3) + 10-hydroxydodecanoic acid + 8-hydroxylauric acid (16899-09-5)

Guidance literature:

With dihydrogen peroxide; tris hydrochloride; full-length cytochrome P₄₅₀ BM-3 (EC 1.14.14.1) F₈₇A mutant; pH=8.2; Further Variations:; Catalysts; Reagents; Product distribution; Enzymatic reaction;

DOI:10.1002/1615-4169(200210)344:9<932::AID-ADSC932>3.0.CO;2-M

upstream raw materials:

Sodium laurate

lauric acid

Downstream raw materials:

C₂₇H₃₉N₅O₆S