1-(3-Tert-butyl-4-hydroxyphenyl)ethanone

Base Information

Chemical Name:1-(3-Tert-butyl-4-hydroxyphenyl)ethanone
CAS No.:16928-01-1
Molecular Formula:C12H16O2
Molecular Weight:192.258
Hs Code.:
DSSTox Substance ID:DTXSID60547688
Nikkaji Number:J2.403.698G
Wikidata:Q82426054
Mol file:16928-01-1.mol

Synonyms:1-(3-tert-butyl-4-hydroxyphenyl)ethanone;16928-01-1;3-tert-butyl-4-hydroxyacetophenone;1-(3-tert-Butyl-4-hydroxyphenyl)ethan-1-one;SCHEMBL1730526;DTXSID60547688;GWWMYURDYQZZSD-UHFFFAOYSA-N;AKOS017516086;1-(3-(tert-Butyl)-4-hydroxyphenyl)ethanone;1-(3-tert-butyl-4-hydroxy-phenyl)-ethanone;1-[3-(tert-Butyl)-4-hydroxyphenyl]-1-ethanone;EN300-1276444;1-(3-(1,1-Dimethylethyl)-4-hydroxyphenyl)ethanone

Suppliers and Price of 1-(3-Tert-butyl-4-hydroxyphenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-(3-Tert-butyl-4-hydroxyphenyl)ethanone

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:192.115029749
Heavy Atom Count:14
Complexity:215

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC(=C(C=C1)O)C(C)(C)C

Technology Process of 1-(3-Tert-butyl-4-hydroxyphenyl)ethanone

There total 4 articles about 1-(3-Tert-butyl-4-hydroxyphenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.1%

: 88-18-6
2-tert-Butylphenol

: 75-36-5
acetyl chloride

: 16928-01-1
1-(3-(tert-butyl)-4-hydroxyphenyl)ethan-1-one

Guidance literature:: aluminum (III) chloride; In toluene; at -45 ℃; for 4.5h;

Reference yield:

: 4-Acetoxy-3-tert.-butyl-acetophenon

: 16928-01-1
1-(3-(tert-butyl)-4-hydroxyphenyl)ethan-1-one

Guidance literature:: 4-Acetoxy-3-tert.-butyl-acetophenon; With methanol; potassium carbonate; at 20 ℃; for 18h;

With hydrogenchloride; In water; pH=5 - 6;

Reference yield:

: 88-18-6
2-tert-Butylphenol

: 16928-01-1
1-(3-(tert-butyl)-4-hydroxyphenyl)ethan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: aluminum (III) chloride / dichloromethane / 1.17 h / -75 - 0 °C / Inert atmosphere

1.2: Cooling with ice

2.1: potassium carbonate; methanol / 18 h / 20 °C

2.2: pH 5 - 6

With methanol; aluminum (III) chloride; potassium carbonate; In dichloromethane;