(4-chloro-3-Methoxypyridin-2-yl)Methanol

Base Information

• Chemical Name: (4-chloro-3-Methoxypyridin-2-yl)Methanol
• CAS No.: 170621-85-9
• Molecular Formula: C7H8ClNO2
• Molecular Weight: 173.59700
• Hs Code.: 2933399090
• Mol file: 170621-85-9.mol

Synonyms:Benzeneacetic acid,4-chloro-3-hydroxy;3-hydroxy-4-chlorophenylacetic acid;4-Chloro-2-hydroxymethyl-3-methoxypyridine;(4-chloro-3-hydroxy-phenyl)-acetic acid;

Chemical Property of (4-chloro-3-Methoxypyridin-2-yl)Methanol

Chemical Property:

• PSA: 42.35000
• LogP: 1.23590

Purity/Quality:

97% ^*data from raw suppliers

(4-Chloro-3-methoxypyridin-2-yl)methanol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-chloro-3-Methoxypyridin-2-yl)Methanol

There total 3 articles about (4-chloro-3-Methoxypyridin-2-yl)Methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

4-chloro-3-methoxy-2-methylpyridine N-oxide (122307-41-9) → 4-Chloro-2-hydroxymethyl-3-methoxypyridine (170621-85-9)

Guidance literature:

4-chloro-3-methoxy-2-methylpyridine N-oxide; With acetic anhydride; at 90 ℃; for 0.383333h;

With potassium hydroxide; In methanol; water; at 0 - 20 ℃; for 0.5h;

Reference yield:

methanolic sodium hydroxide + 4-chloro-3-methoxy-2-methylpyridine N-oxide (122307-41-9) → 4-Chloro-2-hydroxymethyl-3-methoxypyridine (170621-85-9)

Guidance literature:

With acetic anhydride; In methanol; water; acetic acid; Petroleum ether;

Reference yield:

→ 4-Chloro-2-hydroxymethyl-3-methoxypyridine (170621-85-9)

Guidance literature:

upstream raw materials:

4-chloro-3-methoxy-2-methylpyridine N-oxide

Downstream raw materials:

4-chloro-2-chloromethyl-3-methoxypyridine hydrochloride

4-chloro-3-methoxypyridine-2-carbaldehyde