Butanamide, 2-amino-3,3-dimethyl-N-phenyl-, (2S)-

Base Information

Chemical Name:Butanamide, 2-amino-3,3-dimethyl-N-phenyl-, (2S)-
CAS No.:171764-05-9
Molecular Formula:C12H18N2O
Molecular Weight:206.288
Hs Code.:
DSSTox Substance ID:DTXSID60449254
Nikkaji Number:J3.302.364B
Wikidata:Q82268666
Mol file:171764-05-9.mol

Synonyms:Butanamide, 2-amino-3,3-dimethyl-N-phenyl-, (2S)-;171764-05-9;(2S)-2-amino-3,3-dimethyl-N-phenylbutanamide;SCHEMBL8396733;DTXSID60449254;(2S)-N-Phenyl-2-amino-3,3-dimethylbutanamide

Suppliers and Price of Butanamide, 2-amino-3,3-dimethyl-N-phenyl-, (2S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Butanamide, 2-amino-3,3-dimethyl-N-phenyl-, (2S)-

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:206.141913202
Heavy Atom Count:15
Complexity:214

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C(C(=O)NC1=CC=CC=C1)N
Isomeric SMILES:CC(C)(C)[C@@H](C(=O)NC1=CC=CC=C1)N

Technology Process of Butanamide, 2-amino-3,3-dimethyl-N-phenyl-, (2S)-

There total 5 articles about Butanamide, 2-amino-3,3-dimethyl-N-phenyl-, (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 62965-35-9
N-tert-butyloxycarbonyl-L-tert-leucine

: 171764-05-9
(S)-tert-butylglycine phenylamide

Guidance literature:: Multi-step reaction with 2 steps

1: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 4 h / 25 °C

2: trifluoroacetic acid / dichloromethane / 2 h / 25 °C

With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane;
DOI:10.1002/jhet.4443

Reference yield:

: 179533-91-6
(S)-tert-butyl 3,3-dimethyl-1-oxo-1-(phenylamino)butan-2-ylcarbamate

: 171764-05-9
(S)-tert-butylglycine phenylamide

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 25 ℃; for 2h;
DOI:10.1002/jhet.4443

Reference yield:

: 1454610-90-2
(RS)-tert-leucine anilide

: (R)-tert-leucine anilide

: 171764-05-9
(S)-tert-butylglycine phenylamide

Guidance literature:: With (S)-valine anilide imprinted poly(ethylene glycol dimethacrylate-co-methacrylic acid); In dichloromethane; at 24 ℃; for 2h; Optical yield = 9 %ee; Resolution of racemate;
DOI:10.1248/cpb.c12-01044