N3-PEG3-CH2COOtBu

Base Information

Chemical Name:N3-PEG3-CH2COOtBu
CAS No.:172531-36-1
Molecular Formula:C12H23N3O5
Molecular Weight:289.332
Hs Code.:
Mol file:172531-36-1.mol

Synonyms:tert-butyl 11-azido-3,6,9-trioxaundecanoate;tert-butyl 2-[2-(2-(2-azidoethoxy)ethoxy)ethoxy]acetate;tert-butyl 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)acetate;azidotriethylene glycol-Boc;

Suppliers and Price of N3-PEG3-CH2COOtBu

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

BroadPharm
Azido-PEG3-CH2CO2-t-Bu 98%
100 MG
$ 270.00

AK Scientific
1,1-Dimethylethyl11-azido-3,6,9-trioxaundecanoate
1g
$ 334.00

AK Scientific
1,1-Dimethylethyl11-azido-3,6,9-trioxaundecanoate
250mg
$ 128.00

Activate Scientific
N3-PEG3-CH2COOtBu 95+%
1 g
$ 361.00

Acrotein
N3-PEG3-CH2COOtBu 97%
5g
$ 742.50

Acrotein
N3-PEG3-CH2COOtBu 97%
1g
$ 247.50

Total 9 raw suppliers

Chemical Property of N3-PEG3-CH2COOtBu

Chemical Property:

PSA：103.74000
LogP:1.14096
Solubility.:Soluble in DMSO, DCM, DMF

Purity/Quality:

99.90% ^*data from raw suppliers

Azido-PEG3-CH2CO2-t-Bu 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description Azido-PEG3-CH2CO2-t-Bu is a N3 (azide) containing t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Technology Process of N3-PEG3-CH2COOtBu

There total 13 articles about N3-PEG3-CH2COOtBu which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: tert-butyl 2-(2-(2-(2-chloroethoxy)ethoxy)ethoxy)acetate

: 172531-36-1
tert-butyl 2-[2-(2-(2-azidoethoxy)ethoxy)ethoxy]acetate

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 120 ℃; for 3h;

Reference yield: 90.0%

: {2-[2-(2-methanesulfonyloxyethoxy)ethoxy]ethoxy}acetic acid tert-butyl ester

: 172531-36-1
tert-butyl 2-[2-(2-(2-azidoethoxy)ethoxy)ethoxy]acetate

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 60 ℃; for 4h;

Reference yield: 89.0%

: t-butoxycarbonyl bromide

: 86520-52-7
2-[2-(2-azidoethoxy)ethoxy]ethanol

: 172531-36-1
tert-butyl 2-[2-(2-(2-azidoethoxy)ethoxy)ethoxy]acetate

Guidance literature:: With tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide; In water; toluene; at 20 ℃; for 20h;
DOI:10.1039/c2ob06783h