4-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione

Base Information

Chemical Name:4-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione
CAS No.:17280-60-3
Molecular Formula:C15H23NO4
Molecular Weight:281.352
Hs Code.:
Mol file:17280-60-3.mol

Synonyms:cycloheximide;dl-α-Epiisocycloheximid;cycloheximid od. Actidion od. Naramycin A;2,6-Piperidinedione, 4-[2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-;4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxy-ethyl]-piperidine-2,6-dione;racem. Isocycloheximid;(+/-)-2,4-Dimethyl-5-<1-hydroxy-2-(3-glutarimidyl)-ethyl>-cyclohexanon-1;α-epi-Isocycloheximid;

Suppliers and Price of 4-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione

Chemical Property:

PSA：83.47000
LogP:1.37030

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione

There total 7 articles about 4-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 3428-71-5,15676-38-7
C₁₆H₂₆N₄O₄

: 66-81-9,642-81-9,1154-57-0,3226-22-0,4630-75-5,5549-69-9,6258-25-9,6746-42-5,17280-60-3,17973-87-4,18006-33-2,29106-61-4,94130-62-8,94130-63-9,94799-82-3,95272-16-5,95272-17-6,95272-18-7
4-[(S)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxy-ethyl]-piperidine-2,6-dione

Guidance literature:: With acetic acid; sodium nitrite; In water; at 0 ℃; for 0.25h; pH=5;
DOI:10.1016/S0040-4020(01)91400-0

Reference yield:

: 2066-88-8
(2,6-dioxo-piperidin-4-yl)-acetaldehyde

: 93921-42-7
(+)-(2S,4R)-trans-2,4-dimethyl-1-cyclohexanone

: 94130-63-9
(2S,4S,6R,αS)-cycloheximide

: 66-81-9,642-81-9,1154-57-0,3226-22-0,4630-75-5,5549-69-9,6258-25-9,6746-42-5,17280-60-3,17973-87-4,18006-33-2,29106-61-4,94130-62-8,94130-63-9,94799-82-3,95272-16-5,95272-17-6,95272-18-7
(2S,4S,6S,αS)-cycloheximide

: 642-81-9
Cycloheximide

: 66-81-9
Cycloheximide

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; at -70 ℃; for 0.5h; Yield given. Yields of byproduct given;
DOI:10.1271/bbb1961.48.2315

Reference yield:

: 2066-88-8
(2,6-dioxo-piperidin-4-yl)-acetaldehyde

: ((4R,6S)-4,6-Dimethyl-cyclohex-1-enyloxy)-trimethyl-silane

: 94130-63-9
(2S,4S,6R,αS)-cycloheximide

: 66-81-9,642-81-9,1154-57-0,3226-22-0,4630-75-5,5549-69-9,6258-25-9,6746-42-5,17280-60-3,17973-87-4,18006-33-2,29106-61-4,94130-62-8,94130-63-9,94799-82-3,95272-16-5,95272-17-6,95272-18-7
(2S,4S,6S,αS)-cycloheximide

: 642-81-9
Cycloheximide

: 66-81-9
Cycloheximide

Guidance literature:: With titanium tetrachloride; In dichloromethane; Yield given. Yields of byproduct given; 1.) 20 deg C, 5 min, 2.) -45 deg C, 5 min;
DOI:10.1271/bbb1961.48.2315