3-bromo-N,N-bis(trimethylsilyl)propan-1-amine

Base Information

• Chemical Name: 3-bromo-N,N-bis(trimethylsilyl)propan-1-amine
• CAS No.: 172851-95-5
• Molecular Formula: C9H24BrNSi2
• Molecular Weight: 282.371
• DSSTox Substance ID: DTXSID70453165
• Wikidata: Q82274213
• Mol file: 172851-95-5.mol

Synonyms:172851-95-5;3-bromo-N,N-bis(trimethylsilyl)propan-1-amine;N-(3-Bromopropyl)-1,1,1-trimethyl-N-(trimethylsilyl)silanamine;N,N-bis(trimethylsilyl)-3-bromo-1-propylamine;C9H24BrNSi2;Silanamine, N-(3-bromopropyl)-1,1,1-trimethyl-N-(trimethylsilyl)-;SCHEMBL1568300;Br-(CH2)3-N(SiMe3)2;DTXSID70453165;NCITYJREKCYVGX-UHFFFAOYSA-N;XGA85195;AKOS025296405;BS-25150;CS-0132971;3-Bromo-N,N-bis(trimethylsilyl)propan-1-amine, AldrichCPR

Chemical Property of 3-bromo-N,N-bis(trimethylsilyl)propan-1-amine

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 281.06307
• Heavy Atom Count: 13
• Complexity: 135

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)N(CCCBr)[Si](C)(C)C

Technology Process of 3-bromo-N,N-bis(trimethylsilyl)propan-1-amine

There total 4 articles about 3-bromo-N,N-bis(trimethylsilyl)propan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

trimethylsilyl trifluoromethanesulfonate (27607-77-8) + 3-bromopropylamine hydrochloride (5003-71-4) → 3-bromo-N,N’-bis(trimethylsilyl)propan-1-amine (172851-95-5)

Guidance literature:

With triethylamine; In diethyl ether; 0 deg C, 2 h; 4 h, RT;

DOI:10.1016/S0022-328X(97)00516-0

Reference yield:

chloro-trimethyl-silane (75-77-4) + 3-bromopropylamine hydrochloride (5003-71-4) → 3-bromo-N,N’-bis(trimethylsilyl)propan-1-amine (172851-95-5)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 25 ℃; Inert atmosphere;

Reference yield:

chloro-trimethyl-silane (75-77-4) + N-butylammonium bromide (15567-09-6) → 3-bromo-N,N’-bis(trimethylsilyl)propan-1-amine (172851-95-5)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; Cooling with ice;

DOI:10.1021/jm201407j

upstream raw materials:

trimethylsilyl trifluoromethanesulfonate

3-bromopropylamine hydrochloride

chloro-trimethyl-silane

N-butylammonium bromide

Downstream raw materials:

ethyl 2-(3-bromopropylimino)-2-(4-fluorophenyl)acetate

C₁₃H₁₅BrF₅NO₂S

C₁₃H₁₄BrF₂NO₂

C₁₃H₁₆BrNO₂