1'-Ethylspiro[indoline-3,3'-pyrrolidin]-2-one

Base Information

Chemical Name:1'-Ethylspiro[indoline-3,3'-pyrrolidin]-2-one
CAS No.:59022-46-7
Molecular Formula:C₁₃H₁₆N₂O
Molecular Weight:216.283
Hs Code.:
DSSTox Substance ID:DTXSID60974495
Nikkaji Number:J87.100A
ChEMBL ID:CHEMBL3275283
Mol file:59022-46-7.mol

Synonyms:59022-46-7;1'-Ethylspiro[indoline-3,3'-pyrrolidin]-2-one;BRN 0656694;2-Indolinone-3-spiro-3'-(N-ethylpyrrolidine);Spiro(indoline-3,3'-pyrrolidin)-2-one, 1'-ethyl-;CHEMBL3275283;DTXSID60974495;Spiro[3H-indole-3,3'-pyrrolidin]-2(1H)-one,1'-ethyl-;SB65319;LS-146178;1'-Ethylspiro[indole-3,3'-pyrrolidin]-2-ol;Spiro[3H-indole-3,3'-pyrrolidin]-2(1H)-one, 1'-ethyl-

Suppliers and Price of 1'-Ethylspiro[indoline-3,3'-pyrrolidin]-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1'-Ethylspiro[indoline-3,3'-pyrrolidin]-2-one 97%
1g
$ 842.00

Chemenu
1''-Ethylspiro[indoline-3,3''-pyrrolidin]-2-one 97%
1g
$ 795.00

American Custom Chemicals Corporation
2-INDOLINONE-3-SPIRO-3'-(N-ETHYLPYRROLIDINE) 95.00%
5MG
$ 503.86

Alichem
1'-Ethylspiro[indoline-3,3'-pyrrolidin]-2-one
1g
$ 731.88

Total 4 raw suppliers

Chemical Property of 1'-Ethylspiro[indoline-3,3'-pyrrolidin]-2-one

Chemical Property:

Boiling Point:389.3°Cat760mmHg
Flash Point:189.2°C
PSA：35.83000
Density:1.2g/cm³
LogP:1.62510
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:216.126263138
Heavy Atom Count:16
Complexity:304

Purity/Quality:

99% ^*data from raw suppliers

1'-Ethylspiro[indoline-3,3'-pyrrolidin]-2-one 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1CCC2(C1)C3=CC=CC=C3NC2=O

Technology Process of 1'-Ethylspiro[indoline-3,3'-pyrrolidin]-2-one

There total 5 articles about 1'-Ethylspiro[indoline-3,3'-pyrrolidin]-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 64-19-7,77671-22-8
acetic acid

: 397330-95-9
2'-methylthio-2-oxospiro(3H-indole-3,3'-1'-pyrroline)

: 59022-46-7
1'-ethyl-1H-spiro[indole-3,3'-pyrrolidin]-2-one

Guidance literature:: With sodium tetrahydroborate;
DOI:10.1021/ol016824i

Reference yield:

: 15207-62-2
3-[bis(methylsulfanyl)methylene]-2-oxindole

: 59022-46-7
1'-ethyl-1H-spiro[indole-3,3'-pyrrolidin]-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 65 percent / tetrahydrofuran / 10 h / 20 °C

2: 70 percent / KI / acetone / 20 °C

3: 65 percent / NaBH₄

With sodium tetrahydroborate; potassium iodide; In tetrahydrofuran; acetone;
DOI:10.1021/ol016824i

Reference yield:

: 3-[(1-aziridino)(methylthio)methylene]-2-oxindole

: 59022-46-7
1'-ethyl-1H-spiro[indole-3,3'-pyrrolidin]-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / KI / acetone / 20 °C

2: 65 percent / NaBH₄

With sodium tetrahydroborate; potassium iodide; In acetone;
DOI:10.1021/ol016824i