N-(tert-Butyl)pyridine-3-sulfonamide

Base Information

• Chemical Name: N-(tert-Butyl)pyridine-3-sulfonamide
• CAS No.: 17432-06-3
• Molecular Formula: C9H14N2O2S
• Molecular Weight: 214.288
• Hs Code.: 2935009090
• DSSTox Substance ID: DTXSID00545820
• Wikidata: Q82423440
• Mol file: 17432-06-3.mol

Synonyms:N-(tert-Butyl)pyridine-3-sulfonamide;17432-06-3;N-tert-butylpyridine-3-sulfonamide;SCHEMBL858995;DTXSID00545820;AKOS010300010;CS-0214924;EN300-205395;3-Pyridinesulfonamide, N-(1,1-dimethylethyl)-;A907707

Chemical Property of N-(tert-Butyl)pyridine-3-sulfonamide

Chemical Property:

• PSA: 67.44000
• LogP: 2.63010
• Storage Temp.: 2-8°C
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 214.07759887
• Heavy Atom Count: 14
• Complexity: 274

Purity/Quality:

97% ^*data from raw suppliers

N-tert-butylpyridine-3-sulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)NS(=O)(=O)C1=CN=CC=C1

Technology Process of N-(tert-Butyl)pyridine-3-sulfonamide

There total 3 articles about N-(tert-Butyl)pyridine-3-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

Pyridine-3-sulfonyl chloride (16133-25-8) + tert-butylamine (75-64-9) → N-t-butylpyridine-3-sulphonamide (17432-06-3)

Guidance literature:

In chloroform; at 0 ℃; for 0.5h;

Reference yield:

3-pyridinesulfonic acid (636-73-7) → N-t-butylpyridine-3-sulphonamide (17432-06-3)

Guidance literature:

Multi-step reaction with 2 steps

1: phosphorus pentachloride / 3 h / 110 °C

2: 76 percent / CHCl₃ / 0.5 h / 0 °C

With phosphorus pentachloride; In chloroform;

Reference yield:

→ N-t-butylpyridine-3-sulphonamide (17432-06-3)

Guidance literature:

entspr. Chlorid;

upstream raw materials:

Pyridine-3-sulfonyl chloride

tert-butylamine

3-pyridinesulfonic acid

Downstream raw materials:

1,1-diphenyl-3-(N-t-butylsulphonyl)-4-pyridylmethanol

isothiazolo<5,4-c>pyridin-3-one 1,1-dioxide