1-Piperidinecarboxylic acid, 2-propenyl ester

Base Information

• Chemical Name: 1-Piperidinecarboxylic acid, 2-propenyl ester
• CAS No.: 17738-04-4
• Molecular Formula: C9H15NO2
• Molecular Weight: 169.224
• Mol file: 17738-04-4.mol

Synonyms:

Chemical Property of 1-Piperidinecarboxylic acid, 2-propenyl ester

Chemical Property:

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Piperidinecarboxylic acid, 2-propenyl ester

There total 1 articles about 1-Piperidinecarboxylic acid, 2-propenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.1%

piperidine (110-89-4) + allyl phenyl carbonate (16308-68-2) → piperidine-1-carboxylic acid allyl ester (17738-04-4) + phenol (108-95-2,27073-41-2)

Guidance literature:

In N,N-dimethyl-formamide;

Reference yield: 94.0%

piperidine-1-carboxylic acid allyl ester (17738-04-4) + benzylamine (100-46-9) → N-benzyl-N',N'-(1,5-pentamethylenediyl)urea (39531-35-6)

Guidance literature:

benzylamine; With bis(trimethylaluminum)–1,4-diazabicyclo[2.2.2]octane adduct; In toluene; at 40 ℃; for 0.333333h;

piperidine-1-carboxylic acid allyl ester; In toluene; at 90 ℃; for 2h;

DOI:10.1016/j.tet.2018.06.011

Reference yield: 91.0%

piperidine-1-carboxylic acid allyl ester (17738-04-4) + aniline (62-53-3) → 1-(N-phenylcarbamoyl)piperidine (2645-36-5)

Guidance literature:

aniline; With bis(trimethylaluminum)–1,4-diazabicyclo[2.2.2]octane adduct; In toluene; at 40 ℃; for 0.333333h;

piperidine-1-carboxylic acid allyl ester; In toluene; at 90 ℃; for 2h;

DOI:10.1016/j.tet.2018.06.011

upstream raw materials:

piperidine

allyl phenyl carbonate

Downstream raw materials:

N-benzyl-N',N'-(1,5-pentamethylenediyl)urea

1-(N-phenylcarbamoyl)piperidine

N-benzoylpiperidine

1-(3-phenylpropanoyl)piperidine

Refernces