16308-68-2

Usage

Uses

Used in Chemical Synthesis:
ALLYL PHENYL CARBONATE 97 is used as a reactant in the synthesis of various organic compounds. It is particularly useful in the production of indole derivatives through its reaction with (2-alkynyl)phenylisocyanate, catalyzed by a P(0)/Cu(I) system.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, ALLYL PHENYL CARBONATE 97 can be utilized as an intermediate in the synthesis of various drug molecules. Its ability to form indole derivatives makes it a valuable component in the development of potential therapeutic agents.
Used in Research and Development:
ALLYL PHENYL CARBONATE 97 is also used in research and development settings to explore its potential applications in various chemical reactions and to understand its properties and behavior in different reaction conditions. This knowledge can contribute to the advancement of chemical synthesis techniques and the discovery of new compounds with potential applications in various industries.

InChI:InChI=1/C10H10O3/c1-2-8-12-10(11)13-9-6-4-3-5-7-9/h2-7H,1,8H2

Upstream product

• 102-09-0 bis(phenyl) carbonate 
• 107-18-6 allyl alcohol 
• 1885-14-9 phenyl chloroformate 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 108-95-2 phenol 
• 2937-50-0 Allyl chloroformate 

Downstream Products

• 41423-02-3 Carbonic acid 3-(methoxy-dimethyl-silanyl)-propyl ester phenyl ester 
• 16212-05-8 (allylsulfonyl)benzene 
• 28691-72-7 (E)-1-propenyl phenyl sulfone 
• 1746-13-0 allyl phenyl ether 
• 106775-55-7 allyl dibutylcarbamate 
• 108-95-2 phenol 
• 74562-18-8 N,N-Dimethylcarbamidsaeure-(2-propenylester) 
• 36966-57-1 N,N-Diethylcarbamidsaeure-(2-propenylester) 
• 187737-37-7 propene 
• 184292-16-8 (6-aminohexyl)carbamic acid allyl ester 
• 223741-66-0 1-N-(allyloxycarbonyl)-1,2-diaminoethane 
• 117499-16-8 bis(2-tert-butyloxycarbonylaminoethyl)amine 
• 503817-49-0 (2-amino-2-methylpropyl)carbamic acid allyl ester 
• 91583-66-3 phenoxotris(triphenylphosphine)cobalt(I) 

Relevant academic research and scientific papers

A mild ligand-free iron-catalyzed liberation of alcohols from allylcarbonates

Different from most carbonates the allyloxy carbonyl protecting group can be cleaved under neutral conditions using metal catalysis. However, most of the catalysts employed to date are based upon precious metals. Herein we present two protocols for the mild Fe-catalyzed liberation of alcohols from allylcarbonates that are characterized by broad functional group tolerance and exclusive chemoselectivity.

Regioselective iron-catalyzed decarboxylative allylic etherification

[Chemical Equation Presented] An anionic iron complex catalyzes the decarboxylative allylation of phenols to form allylic ethers in high yield. The allylation is regioselective rather than regiospecific. This suggests that the allylation proceeds through π-allyl iron intermediates in contrast to related allylations of carbon nucleophiles that have been proposed to proceed via π-allyl complexes. Ultimately, iron catalysts have the potential to replace more expensive palladium catalysts that are typically utilized for decarboxylative couplings.

Expanding the scope and orthogonality of PNA synthesis

Peptide nucleic acids (PNAs) hybridize to natural oligonucleotides according to Watson and Crick base-pairing rules. The robustness of PNA oligomers and ease of synthesis have made them an attractive platform to encode small or macromolecules for microarr

Enzymatic resolution of a secondary amine using novel acylating reagents

Phenyl allylcarbonates are useful acylating agents for the enzymatic resolution of 1-methyl tetrahydroisoquinoline.

A bimetallic catalyst and dual role catalyst: Synthesis of N-(alkoxycarbonyl)indoles from 2-(alkynyl)phenylisocyanates

3-Allyl-N-(alkoxycarbonyl)indoles are synthesized via the reaction of 2-(alkynyl)phenylisocyanates and allyl carbonates in the presence of Pd(PPh3)4 (1 mol %) and CuCl (4 mol %) bimetallic catalyst. It is most probable that Pd0

Selective synthesis of carbamate protected polyamines using alkyl phenyl carbonates

Utilising alkyl phenyl carbonates, an economical, practical and versatile method for selective Boc, Cbz and Alloc protection of polyamines has been developed. This method allows Boc, Cbz and Alloc protection of primary amines in the presence of secondary amines by reaction of the polyamines with the alkyl phenyl carbonates. Also, this method allows mono carbamate protection of simple symmetrical aliphatic α,ω-alkanediamines in high yields with respect to the diamine. Finally, the method allows selective carbamate protection of a primary amine located on a primary carbon in the presence of a primary amine located on a secondary or a tertiary carbon in excellent yields.

Derivatives of N-HALS-substituted amic acid hydrazides

N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides contain a light stabilizing group, a heat stabilizing group and an amic acid hydrazide functionality in the same molecule. The amic acid hydrazide functionality in the compounds enhances the photoox

Synthesis of allylic aryl ethers via palladium-catalyzed decarboxylation of allylic aryl carbonates

Allylic aryl ethers are readily prepared in high yield by the palladium-catalyzed decarboxylation of allylic aryl carbonates.