3,7,8-Trimethoxy-2-methyl-5-(5-phenylpentyl)quinolin-4(1H)-one

Base Information

Chemical Name:3,7,8-Trimethoxy-2-methyl-5-(5-phenylpentyl)quinolin-4(1H)-one
CAS No.:69905-17-5
Molecular Formula:C₂₄H₂₉NO₄
Molecular Weight:395.499
Hs Code.:
Mol file:69905-17-5.mol

Synonyms:3,7,8-Trimethoxy-2-methyl-5(5'-phenylpentyl)-4-quinolinone;3,7,8-Trimethoxy-2-methyl-5-(5-phenyl-pentyl)-1H-quinolin-4-one;

Suppliers and Price of 3,7,8-Trimethoxy-2-methyl-5-(5-phenylpentyl)quinolin-4(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3,7,8-Trimethoxy-2-methyl-5-(5-phenylpentyl)quinolin-4(1H)-one

Chemical Property:

Melting Point:134 - 136 °C
PSA：60.55000
LogP:4.81780

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3,7,8-Trimethoxy-2-methyl-5-(5-phenylpentyl)quinolin-4(1H)-one

There total 15 articles about 3,7,8-Trimethoxy-2-methyl-5-(5-phenylpentyl)quinolin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 90766-55-5
4-acetoxy-6-bromo-3-methoxy-2-nitrobenzaldehyde

: 69905-17-5
3,7,8-trimethoxy-2-methyl-5-(5'-phenyl-1'-pentyl)quinoline-4(1H)-one

Guidance literature:: Multi-step reaction with 8 steps

1.1: sodium hydroxide; water / 1 h / 40 °C / Inert atmosphere

2.1: potassium carbonate / N,N-dimethyl-formamide / 5 h / 50 °C / Inert atmosphere

3.1: chromium(VI) oxide; sulfuric acid; water / acetone / 1 h / 20 °C

4.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 40 °C / Inert atmosphere

4.2: 1 h / 20 - 50 °C / Inert atmosphere

5.1: potassium carbonate; palladium diacetate; 1,1'-bis(di-tertbutylphosphino)ferrocene / water; toluene / 18 h / 80 °C / Inert atmosphere

6.1: nickel boride; hydrogen / methanol / 0.08 h

6.2: 0.5 h / 70 °C

7.1: acetic acid / 0.42 h / 150 °C / Inert atmosphere; Microwave irradiation

8.1: potassium carbonate / isopropyl alcohol / 0.25 h / 20 °C / Inert atmosphere

8.2: 3.5 h / 50 °C / Inert atmosphere

With chromium(VI) oxide; 1,1'-bis(di-tertbutylphosphino)ferrocene; sulfuric acid; nickel boride; water; hydrogen; palladium diacetate; potassium carbonate; acetic acid; sodium hydroxide; In methanol; water; N,N-dimethyl-formamide; isopropyl alcohol; acetone; toluene; 5.1: |Suzuki-Miyaura Coupling;
DOI:10.1055/s-0039-1690164

Reference yield:

: 109305-96-6
6-bromo-3,4-dimethoxy-2-nitrobenzaldehyde

: 69905-17-5
3,7,8-trimethoxy-2-methyl-5-(5'-phenyl-1'-pentyl)quinoline-4(1H)-one

Guidance literature:: Multi-step reaction with 6 steps

1.1: chromium(VI) oxide; sulfuric acid; water / acetone / 1 h / 20 °C

2.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 40 °C / Inert atmosphere

2.2: 1 h / 20 - 50 °C / Inert atmosphere

3.1: potassium carbonate; palladium diacetate; 1,1'-bis(di-tertbutylphosphino)ferrocene / water; toluene / 18 h / 80 °C / Inert atmosphere

4.1: nickel boride; hydrogen / methanol / 0.08 h

4.2: 0.5 h / 70 °C

5.1: acetic acid / 0.42 h / 150 °C / Inert atmosphere; Microwave irradiation

6.1: potassium carbonate / isopropyl alcohol / 0.25 h / 20 °C / Inert atmosphere

6.2: 3.5 h / 50 °C / Inert atmosphere

With chromium(VI) oxide; 1,1'-bis(di-tertbutylphosphino)ferrocene; sulfuric acid; nickel boride; water; hydrogen; palladium diacetate; potassium carbonate; acetic acid; In methanol; water; N,N-dimethyl-formamide; isopropyl alcohol; acetone; toluene; 3.1: |Suzuki-Miyaura Coupling;
DOI:10.1055/s-0039-1690164

Reference yield:

: 36225-16-8
6-bromo-4-hydroxy-3-methoxy-2-nitrobenzaldehyde

: 69905-17-5
3,7,8-trimethoxy-2-methyl-5-(5'-phenyl-1'-pentyl)quinoline-4(1H)-one

Guidance literature:: Multi-step reaction with 7 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 5 h / 50 °C / Inert atmosphere

2.1: chromium(VI) oxide; sulfuric acid; water / acetone / 1 h / 20 °C

3.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 40 °C / Inert atmosphere

3.2: 1 h / 20 - 50 °C / Inert atmosphere

4.1: potassium carbonate; palladium diacetate; 1,1'-bis(di-tertbutylphosphino)ferrocene / water; toluene / 18 h / 80 °C / Inert atmosphere

5.1: nickel boride; hydrogen / methanol / 0.08 h

5.2: 0.5 h / 70 °C

6.1: acetic acid / 0.42 h / 150 °C / Inert atmosphere; Microwave irradiation

7.1: potassium carbonate / isopropyl alcohol / 0.25 h / 20 °C / Inert atmosphere

7.2: 3.5 h / 50 °C / Inert atmosphere

With chromium(VI) oxide; 1,1'-bis(di-tertbutylphosphino)ferrocene; sulfuric acid; nickel boride; water; hydrogen; palladium diacetate; potassium carbonate; acetic acid; In methanol; water; N,N-dimethyl-formamide; isopropyl alcohol; acetone; toluene; 4.1: |Suzuki-Miyaura Coupling;
DOI:10.1055/s-0039-1690164