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Grindelic acid

Base Information Edit
  • Chemical Name:Grindelic acid
  • CAS No.:1438-57-9
  • Molecular Formula:C20H32 O3
  • Molecular Weight:320.4663
  • Hs Code.:
  • UNII:4QX9FCD1IN
  • Nikkaji Number:J17.207C
  • Wikidata:Q27260380
  • Metabolomics Workbench ID:129034
  • ChEMBL ID:CHEMBL2419211
  • Mol file:1438-57-9.mol
Grindelic acid

Synonyms:grindelic acid

Suppliers and Price of Grindelic acid
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • (-)-GrindelicAcid
  • 1mg
  • $ 210.00
  • TRC
  • (-)-GrindelicAcid
  • 10mg
  • $ 1680.00
  • Sigma-Aldrich
  • Grindelic acid ≥95% (LC/MS-ELSD)
  • 1mg
  • $ 245.00
Total 2 raw suppliers
Chemical Property of Grindelic acid Edit
Chemical Property:
  • Melting Point:100-101° 
  • Boiling Point:434.7°Cat760mmHg 
  • Flash Point:145.8°C 
  • PSA:46.53000 
  • Density:1.07g/cm3 
  • LogP:4.95160 
  • Storage Temp.:?20°C 
  • XLogP3:4.1
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:2
  • Exact Mass:320.23514488
  • Heavy Atom Count:23
  • Complexity:549
Purity/Quality:

97% *data from raw suppliers

(-)-GrindelicAcid *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC1=CCC2C(CCCC2(C13CCC(O3)(C)CC(=O)O)C)(C)C
  • Isomeric SMILES:CC1=CC[C@@H]2[C@@]([C@@]13CC[C@@](O3)(C)CC(=O)O)(CCCC2(C)C)C
  • Uses (-)-Grindelic Acid is a natural diterpene with potential pharmaceutical applications including Nox4 inhibition and antitumor activity.
Technology Process of Grindelic acid

There total 2 articles about Grindelic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With potassium hydroxide; In methanol; water; for 48h; Ambient temperature;
DOI:10.1021/jo960547p

Reference yield:

Guidance literature:
aus Methyl-grindelat 1b durch Hydrolyse;
Guidance literature:
acetone; benzylamine; In methanol; for 3h;
(-)-grindelic acid; Benzyl isocyanide; In methanol; for 24h;
DOI:10.1016/j.ejmech.2013.06.013
Refernces Edit
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