(3-Chloroprop-1-yn-1-yl)(triethyl)silane

Base Information

Chemical Name:(3-Chloroprop-1-yn-1-yl)(triethyl)silane
CAS No.:17889-26-8
Molecular Formula:C9H17ClSi
Molecular Weight:188.772
Hs Code.:
DSSTox Substance ID:DTXSID00523709
Wikidata:Q82389997

Synonyms:17889-26-8;(3-Chloroprop-1-yn-1-yl)(triethyl)silane;DTXSID00523709;triethyl(3-chloropropyn-1-yl)silane

Suppliers and Price of (3-Chloroprop-1-yn-1-yl)(triethyl)silane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (3-Chloroprop-1-yn-1-yl)(triethyl)silane

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:4
Exact Mass:188.0788048
Heavy Atom Count:11
Complexity:151

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC[Si](CC)(CC)C#CCCl

Technology Process of (3-Chloroprop-1-yn-1-yl)(triethyl)silane

There total 1 articles about (3-Chloroprop-1-yn-1-yl)(triethyl)silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 617-86-7
triethylsilane

: 624-65-7
2-propynyl chloride

: 994-30-9
triethylsilyl chloride

: 17898-21-4
triethylallylsilane

: 83053-45-6
triethyl(propen-1-yl)silane

: 17889-26-8
(3-chloroprop-1-ynyl)triethylsilane

Guidance literature:: With dihydrogen hexachloroplatinate; iodine; In tetrahydrofuran; at 20 ℃; Further byproducts given;
DOI:10.1007/BF00954045

Reference yield:

: 17889-26-8
(3-chloroprop-1-ynyl)triethylsilane

: N-carbobenzyloxy-6-(tert-butyldimethylsilyloxymethyl)-2-triethylsilyl-L-tryptophan tert-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: aq. KOH; O⁽⁹⁾-allyl-N-2',3',4'-trifluorobenzylcinchonidinium bromide / toluene; CHCl₃ / 2 h / 0 °C

2: aq. HCl / tetrahydrofuran / 0.83 h / 0 °C

3: 203 mg / NaHCO₃ / dioxane; H₂O / 1.75 h / 20 °C

4: 58 percent / LiCl; Na₂CO₃ / Pd(OAc)2 / dimethylformamide / 23 h / 90 °C

With hydrogenchloride; potassium hydroxide; O⁽⁹⁾-All-N-(2',3',4'-trifluorobenzyl)hydrocinchonidinium bromide; sodium hydrogencarbonate; sodium carbonate; lithium chloride; palladium diacetate; In tetrahydrofuran; 1,4-dioxane; chloroform; water; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ol035236x

Reference yield:

: 17889-26-8
(3-chloroprop-1-ynyl)triethylsilane

: 81477-94-3
N-(diphenylmethylene)glycine tert-butyl ester

: tert-butyl (2R)-2-(benzhydrylidene-amino)-5-triethylsilyl-4-pentynoate

: 612825-71-5
tert-butyl (2S)-2-(benzhydrylidene-amino)-5-triethylsilyl-4-pentynoate

Guidance literature:: With potassium hydroxide; O⁽⁹⁾-All-N-(2',3',4'-trifluorobenzyl)hydrocinchonidinium bromide; In chloroform; toluene; at 0 ℃; for 2h; Title compound not separated from byproducts;
DOI:10.1021/ol035236x