5-Benzofuranol, 2,4,6,7-tetramethyl-

Base Information

• Chemical Name: 5-Benzofuranol, 2,4,6,7-tetramethyl-
• CAS No.: 85979-45-9
• Molecular Formula: C₁₂H₁₄O₂
• Molecular Weight: 190.242
• DSSTox Substance ID: DTXSID10235321
• Wikidata: Q83117224
• Mol file: 85979-45-9.mol

Synonyms:BRN 0137848;5-Benzofuranol, 2,4,6,7-tetramethyl-;2,4,6,7-Tetramethyl-5-benzofuranol;85979-45-9;4-17-00-01500 (Beilstein Handbook Reference);SCHEMBL8863741;DTXSID10235321;LS-35314

Chemical Property of 5-Benzofuranol, 2,4,6,7-tetramethyl-

Chemical Property:

• Vapor Pressure: 0.000299mmHg at 25°C
• Boiling Point: 311.9°Cat760mmHg
• Flash Point: 142.4°C
• Density: 1.119g/cm³
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 190.099379685
• Heavy Atom Count: 14
• Complexity: 216

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC2=C(O1)C(=C(C(=C2C)O)C)C

Technology Process of 5-Benzofuranol, 2,4,6,7-tetramethyl-

There total 10 articles about 5-Benzofuranol, 2,4,6,7-tetramethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,4-Dihydroxy-2,3,5-trimethyl-6-(pentan-2,4-dion-3-yl)benzol (69466-12-2) → 5-hydroxy-2,4,6,7-tetramethylbenzofuran (85979-45-9)

Guidance literature:

With hydrogenchloride; ethanol;

DOI:10.1021/ja01858a036

Reference yield:

3-(2,5-dihydroxy-3,4,6-trimethyl-phenyl)-heptadecane-2,4-dione (855892-92-1) → 5-hydroxy-2,4,6,7-tetramethylbenzofuran (85979-45-9) + 4,6,7-trimethyl-2-tridecyl-benzofuran-5-ol

Guidance literature:

With sodium hydroxide; anschliessend behandeln mit wss. Salzsaeure;

Reference yield:

2,3,5-Trimethyl-1,4-benzoquinone (935-92-2) + sodium ethyl acetylacetate enolate (1007476-32-5) → 5-hydroxy-2,4,6,7-tetramethylbenzofuran (85979-45-9) + 2,3-dihydro-5-hydroxy-4,6,7-trimethyl-2(3H)-benzofuranone (59614-71-0)

Guidance literature:

With ethanol; Behandeln des Reaktionsgemisches mit wss. Salzsaeure und anschliessenden Erhitzen mit Wasserdampf;

DOI:10.1021/ja01295a029

upstream raw materials:

ethanol

2,3,5-Trimethyl-1,4-benzoquinone

sodium ethyl acetylacetate enolate

1-methyl-4-nitrosobenzene