6-fluorochrysene

Base Information

• Chemical Name: 6-fluorochrysene
• CAS No.: 3799-55-1
• Molecular Formula: C₁₈H₁₁F
• Molecular Weight: 246.284
• Mol file: 3799-55-1.mol

Synonyms:6-Fluorochrysene;NSC 80184

Chemical Property of 6-fluorochrysene

Chemical Property:

• Vapor Pressure: 1.61E-07mmHg at 25°C
• Boiling Point: 439.7°C at 760 mmHg
• Flash Point: 185.6°C
• Density: 1.256g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-fluorochrysene

There total 14 articles about 6-fluorochrysene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

1-(2-fluoro-2-phenylvinyl)naphthalene → 6-fluorochrysene (3799-55-1)

Guidance literature:

With iodine; methyloxirane; In benzene; for 8h; Inert atmosphere; Irradiation;

DOI:10.1021/acs.joc.5b02580

Reference yield: 51.0%

1-(2,2-difluorovinyl)-2-phenylnaphthalene → 6-fluorochrysene (3799-55-1)

Guidance literature:

With dimethylsulfide borane complex; silver trifluoromethanesulfonate; palladium dichloride; at 0 - 60 ℃; for 2h;

DOI:10.1021/ol503759d

Reference yield:

α-naphthol (90-15-3) → 6-fluorochrysene (3799-55-1)

Guidance literature:

Multi-step reaction with 5 steps

1.1: N-Bromosuccinimide; diisopropylamine / dichloromethane / 23 h / 20 °C / Reflux

2.1: pyridine / dichloromethane / 4 h / 0 - 20 °C

3.1: potassium phosphate; bis-triphenylphosphine-palladium(II) chloride; lithium bromide / toluene / 22 h / 20 °C / Reflux

4.1: N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium / tetrahydrofuran; diethyl ether; cyclohexane; hexane / 0.33 h / -110 °C

4.2: 0.5 h / -100 °C

4.3: 16.5 h / Reflux

5.1: dimethylsulfide borane complex; silver trifluoromethanesulfonate; palladium dichloride / 2 h / 0 - 60 °C

With pyridine; bis-triphenylphosphine-palladium(II) chloride; potassium phosphate; N-Bromosuccinimide; N,N,N,N,-tetramethylethylenediamine; dimethylsulfide borane complex; sec.-butyllithium; silver trifluoromethanesulfonate; diisopropylamine; lithium bromide; palladium dichloride; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; cyclohexane; toluene;

DOI:10.1021/ol503759d

upstream raw materials:

1-Indanol

1-chloroindane

1-cyanoindane

1-phenyl-2,3-dihydro-1H-indene-1-carbonitrile

Refernces

• 1、 Fuchibe, Kohei,Morikawa, Toshiyuki,Shigeno, Kento,Fujita, Takeshi,Ichikawa, Junji. "Pinpoint-fluorinated phenacenes: New synthesis and solubility enhancement strategies". . p. 1126 - 1129. Retrieved 2015/03/14.