Triisopropanolamine

Base Information

• Chemical Name: Triisopropanolamine
• CAS No.: 122-20-3
• Deprecated CAS: 2488591-40-6
• Molecular Formula: C9H21NO3
• Molecular Weight: 191.271
• Hs Code.: 2922.19
• European Community (EC) Number: 204-528-4
• ICSC Number: 0592
• NSC Number: 4010
• UN Number: 3259
• UNII: W9EN9DLM98
• DSSTox Substance ID: DTXSID5021415
• Nikkaji Number: J3.616A
• Wikipedia: Triisopropanolamine
• Wikidata: Q1729503
• RXCUI: 1426368
• ChEMBL ID: CHEMBL1877948
• Mol file: 122-20-3.mol

Synonyms:TiPlA;triisopropanolamine;triisopropanolamine citrate;triisopropanolamine hydrochloride;tris(2-hydroxypropyl)amine

Chemical Property of Triisopropanolamine

Chemical Property:

• Appearance/Colour: white to slightly yellow powder
• Vapor Pressure: 0.000148mmHg at 25°C
• Melting Point: 48-52 °C(lit.)
• Refractive Index: 1.4200 (estimate)
• Boiling Point: 296.4 °C at 760 mmHg
• PKA: 14.37±0.20(Predicted)
• Flash Point: 167 °C
• PSA: 63.93000
• Density: 1.0 g/cm³
• LogP: -0.56920
• Storage Temp.: Store below +30°C.
• Sensitive.: Hygroscopic
• Water Solubility.: Soluble
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 191.15214353
• Heavy Atom Count: 13
• Complexity: 108

Purity/Quality:

99% ^*data from raw suppliers

Triisopropanolamine (mixture of isomer) >98.0%(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36-52/53
• Safety Statements: 26-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Amines, Aliphatic
• Canonical SMILES: CC(CN(CC(C)O)CC(C)O)O
• Inhalation Risk: Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered.
• Effects of Short Term Exposure: The substance is severely irritating to the eyes. The substance is irritating to the skin and respiratory tract.
• Description: Triisopropanolamine (TIPA), a tertiary alkanolamine, is majorly used as a grinding chemical that reduces agglomeration in the ball milling process and changes the particle distribution of the finished cement.
• Uses: Triisopropanolamine is used as an emulsifying agent. Triisopropanolamine is an amine used for a variety of industrial applications including as an emulsifier, stabilizer, and chemical intermediate. It is also used to neutralize acidic components of some herbicides.Triisopropanolamine is an aminoalcohol and belongs to the group of alkanolamines. It is majorly used as a grinding chemical that reduces agglomeration in the ball milling process and changes the particle distribution of the finished cement. Major applications include water-based coating applications and agricultural products. Additional applications are antistat agents for polymers, corrosion inhibitor, electrodeposition/electrocoating, lubricants, paper, pigment dispersion, plastics, polyurethane additive, reaction intermediates, rubber curing, surfactants, mineral dispersion, and urethanes.

Technology Process of Triisopropanolamine

There total 5 articles about Triisopropanolamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3,7,10-tetramethyl-2,8,9-trioxa-5-aza-1-sila-bicyclo[3.3.3]undecane (64235-17-2,64235-28-5,71229-51-1) → triisopropanolamine (122-20-3) + methylsilanetriol (2445-53-6)

Guidance literature:

With disodium hydrogenphosphate; potassium dihydrogenphosphate; at 50 ℃; Rate constant; Mechanism; hydrolysis in neutral medium;

DOI:10.1007/BF00960256

Reference yield:

methyloxirane (75-56-9,16033-71-9) → triisopropanolamine (122-20-3)

Guidance literature:

With ammonia; water; at 100 ℃; under 44130.5 - 58840.6 Torr;

Reference yield:

1-amino-2-propanol hydrochloride (7780-04-3) → triisopropanolamine (122-20-3)

Guidance literature:

With sodium methylate; In methanol;

upstream raw materials:

methyloxirane

1,3,7,10-tetramethyl-2,8,9-trioxa-5-aza-1-sila-bicyclo[3.3.3]undecane

1-amino-2-propanol hydrochloride

Downstream raw materials:

tris-(2-chloro-propyl)-amine

Triisopropylamin-borat

aniline

Azobenzene

Refernces

• 1、 -. "Preparation method of isopropanolamine". Paragraph 0019. . Retrieved 2017/01/23.
• 2、 -. "Method of preparing bioerodible polymers having pH sensitivity in the acid range and resulting product". . . Retrieved 2008/06/13.